7699-30-1Relevant articles and documents
A chemical model for the enzymatic mono de-alkylation of (methyl and ethyl) parathion by glutathione-S-transferase
Maturano, Marie Dolores,Bongibault, Véronique,Willson, Michèle,Klaébé, Alain,Fournier, Didier
, p. 17241 - 17246 (2007/10/03)
The NMR study of the reaction of methylparathion with thiol (glutathione) and a tertiary amine shows unambiguously a sequential transfer of the methyl group firstly to the amine and secondly to the thiol. The reaction stops after a single demethylation. This observation may account for regiospecificity of some glutathione S-transferases.