77087-78-6

Basic information

• Product Name: 1,3-Dihydro-2'-phenylspiro<2H-inden-2,4'-<2>oxazolin>-5'-on
• Synonyms: 1,3-Dihydro-2'-phenylspiro<2H-inden-2,4'-<2>oxazolin>-5'-on
• CAS NO: 77087-78-6
• Molecular Weight: 263.296
• Mol File: 77087-78-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-Dihydro-2'-phenylspiro<2H-inden-2,4'-<2>oxazolin>-5'-on(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dihydro-2'-phenylspiro<2H-inden-2,4'-<2>oxazolin>-5'-on(77087-78-6)
• EPA Substance Registry System: 1,3-Dihydro-2'-phenylspiro<2H-inden-2,4'-<2>oxazolin>-5'-on(77087-78-6)

Safety Data

• Hazardous Substances Data: 77087-78-6(Hazardous Substances Data)

Upstream product

• 495-69-2 Hippuric Acid 
• 1199-01-5 2-phenylazlactone 
• 91-13-4 α,α'-dibromo-o-xylene 

Downstream Products

• 77087-86-6 2-Benzoylamino-2,3-dihydro-2-indencarbonsaeure 

Relevant articles and documents

α-Amino Acids as Nucleophilic Acyl Equivalents, IV. Synthesis of Symmetrical Ketones by Means of 2-Phenyl-2-oxazolin-5-one

2-Phenyl-2-oxazolin-5-one (2), itself easily derivable from hippuric acid (1), on reaction with allyl, benzyl or phenacyl halides undergoes 4,4-disubstitution, if the reaction is conducted in dipolar aprotic solvents in presence of weak bases.Hydrolysis of the resulting oxazolinones 3 leads to α,α-dialkylaed hippuric acids 4, which may be oxidized to symmetrical ketones 5 by means of lead tetraacetate.