77476-81-4Relevant articles and documents
SYNTHESIS OF 5-FLUOROURACIL NUCLEOSIDES OF D-GLUCOPYRANURONIC ACID
Kulinkovich, L. N.,Timoshchuk, V. A.
, p. 1483 - 1485 (2007/10/02)
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77476-81-4
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Basic information
- Product Name: 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate
- Synonyms: 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate
- CAS NO:77476-81-4
- Molecular Formula: C17H19FN2O11
- Molecular Weight: 446.3379632
- EINECS: N/A
- Product Categories: Bases & Related Reagents;Glucuronides;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Glucuronides, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File: 77476-81-4.mol
- Article Data: 2
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate(CAS DataBase Reference)
- NIST Chemistry Reference: 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate(77476-81-4)
- EPA Substance Registry System: 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate(77476-81-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 77476-81-4(Hazardous Substances Data)
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77476-81-4 Usage
Description
5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate is a chemical compound derived from 5-Fluorouracil, a widely used chemotherapeutic agent. 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate is characterized by its off-white solid appearance and is a derivative of 5-Fluorouracil N-β-D-Glucuronide (F596010), which is known for its potential applications in the field of cancer treatment.Uses
Used in Pharmaceutical Industry:5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate is used as an intermediate compound for the development of novel anticancer drugs. Its unique structure allows for the creation of new drug candidates that can potentially enhance the effectiveness of cancer treatments and overcome resistance issues associated with existing therapies.
Used in Research and Development:
In the field of cancer research, this compound serves as a valuable tool for understanding the mechanisms of action and resistance to 5-Fluorouracil. By studying the properties and interactions of 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate, researchers can gain insights into the development of more effective cancer treatments and drug delivery systems.
Used in Drug Delivery Systems:
Similar to Gallotannin, 5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate can be employed in the development of innovative drug delivery systems. These systems aim to improve the bioavailability, delivery, and therapeutic outcomes of anticancer drugs, ultimately enhancing their efficacy against cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 77476-81-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,4,7 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.Calculate Digit Verification of CAS Registry Number 77476-81:
(7*7)+(6*7)+(5*4)+(4*7)+(3*6)+(2*8)+(1*1)=174
174 % 10 = 4
So 77476-81-4 is a valid CAS Registry Number.
77476-81-4Upstream product
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77476-81-4Downstream Products
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5-Fluorouracil N-β-D-Glucuronide Methyl Ester, 2,3,4-Triacetate
