77611-30-4

Basic information

• Product Name: (25R)-26-hydroxy-16-oxocholesterol
• CAS NO: 77611-30-4
• Molecular Weight: 416.645
• Mol File: 77611-30-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (25R)-26-hydroxy-16-oxocholesterol(CAS DataBase Reference)
• NIST Chemistry Reference: (25R)-26-hydroxy-16-oxocholesterol(77611-30-4)
• EPA Substance Registry System: (25R)-26-hydroxy-16-oxocholesterol(77611-30-4)

Safety Data

• Hazardous Substances Data: 77611-30-4(Hazardous Substances Data)

Upstream product

• 1061-54-7 Diosgenin monoacetate 
• 105078-96-4 (25R)-3β,26-O-bis-p-nitrobenzoyl-16β,26-dihydroxycholesterol 
• 31327-56-7 (25R)-cholest-5-ene-3β,16β,26-triol 
• 105078-97-5 (25R)-3β,26-O-bis-p-nitrobenzoyl-16-oxo-26-hydroxycholesterol 
• 468-99-5 kryptogenin 

Downstream Products

• 13095-61-9 (25R)-cholest-5-ene-3β,26-diol 
• 56792-57-5 (3S,8S,9S,10R,13R,14S,17R)-17-((1R,5R)-1,5-Dimethyl-6-trityloxy-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol 
• 105078-99-7 3-O-acetyl-26-hydroxy-26-O-tosylcholesterol 
• 105078-98-6 (25S)-3β-acetoxy-26-trityloxycholest-5-ene 

Relevant articles and documents

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Synthesis of (25S)-2H1>Cholesterol and 1H N.m.r. Signal Assignments of the pro-R and pro-S Methyl Groups at C-25

(25S)-2H1>Cholesterol (11) has been prepared from diosgenin (1), and the absolute configuration at C-25 of the crucial intermediate , (25R)-26-hydroxycholesterol (6), has been identified by X-ray crystallographic analysis.The two methyl groups at C-25 of cholesterol have been examined by 1H n.m.r. spectroscopy and the two sets of doublet methyl signals due to 27-H and 26-H have been observed at δH 0.862 and 0.866 downfield from the internal reference.The former was assigned to 27-H, the pro-R methyl group attached at C-25, and the latter to 26-H, the pro-S methyl group attached at C-25.The 13C n.m.r. signal assignments of the methyl groups at C-25 reported by Popjak were confirmed on the basis of the signals of the deuteriated cholesterol (11).