77838-08-5

Basic information

• Product Name: N-hydroxybenzotriazole ester of N-Boc-6-aminohexanoic acid
• Synonyms: N-hydroxybenzotriazole ester of N-Boc-6-aminohexanoic acid
• CAS NO: 77838-08-5
• Molecular Weight: 348.402
• Mol File: 77838-08-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-hydroxybenzotriazole ester of N-Boc-6-aminohexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-hydroxybenzotriazole ester of N-Boc-6-aminohexanoic acid(77838-08-5)
• EPA Substance Registry System: N-hydroxybenzotriazole ester of N-Boc-6-aminohexanoic acid(77838-08-5)

Safety Data

• Hazardous Substances Data: 77838-08-5(Hazardous Substances Data)

Upstream product

• 6404-29-1 6-(tert-butoxycarbonylamino)hexanoic acid 
• 2592-95-2 benzotriazol-1-ol 
• 54769-59-4 N-hydroxybenzotriazole ester of benzenesulfonic acid 

Downstream Products

• 69936-59-0 p-(N-Boc-6-aminohexanoyl)amino-phenyl-β-L-fucopyranoside 
• 154561-43-0 Boc-Acp-Tyr-OMe 
• 1263819-90-4 N-((N-chlorambucilylamino)hexanoyl)-p-hydroxyphenyl-L-p-tyrosinamide 
• 1260612-26-7 N-[6-(N-chlorambucilamino)hexanoyl]-L-p-tyrosine methyl ester 
• 1263819-88-0 N-((N-Boc-amino)hexanoyl)-p-hydroxyphenyl-L-p-tyrosinamide 

Relevant articles and documents

ANTICANCER AGENTS BASED ON AMINO ACID DERIVATIVES

The present invention provides compounds of formula (I): in which T is L or -A-NH-C(O)-L-; L is -(CH2)n- or -(CH2)p-Z-; A is -(CH2)m- or an alkyl component of a naturally occurring amino acid; R is -CO2R1, -CH2OH, -C(O)NH(hydroxyphenyl) or C(S)NH(hydroxyphenyl); R1 is H or is C1-C12 alkyl; X is -OH, OSO2R2, -Cl, -Br, or -I; R2 is C1-C12 alkyl or -CF3; Z is phenyl or naphthyl; m is an integer having a value of 1 to 20; n is an integer having a value of 1 to 20; and p is an integer having a value of 1 to 20 or an enantiomer, diastereoisomer, racemic mixture, pharmaceutically acceptable salt, solvate or prodrug thereof. These compounds can be useful as anticancer agents.

COVALENT ADDITION OF BIOLOGICALLY ACTIVE SUBSTANCES TO POLYMERS IV. SYNTHESIS OF AFFINITY ADSORBENTS CONTAINING L-FUCOSE DERIVATIVES

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