779295-89-5Relevant articles and documents
Improving specificity vs bacterial thymidylate synthases through N-dansyl modulation of didansyltyrosine
Tondi, Donatella,Venturelli, Alberto,Ferrari, Stefania,Ghelli, Stefano,Costi, M. Paola
, p. 913 - 916 (2007/10/03)
N,O-Didansyl-L-tyrosine (DDT) represented the starting lead for further development of novel non-substrate-like inhibitors of bacterial thymidylate synthase. The N-dansyl structure modulation led to a submicromolar inhibitor of Lactobacillus casei TS (LcT