78346-07-3

Basic information

• Product Name: 6-{4-[N-cyclohexylmethyl-N-(3-hydroxypropyl)aminocarbonyl]butoxy}-3,4-dihydrocarbostyril
• Synonyms: 6-{4-[N-cyclohexylmethyl-N-(3-hydroxypropyl)aminocarbonyl]butoxy}-3,4-dihydrocarbostyril
• CAS NO: 78346-07-3
• Molecular Weight: 416.561
• Mol File: 78346-07-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-{4-[N-cyclohexylmethyl-N-(3-hydroxypropyl)aminocarbonyl]butoxy}-3,4-dihydrocarbostyril(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{4-[N-cyclohexylmethyl-N-(3-hydroxypropyl)aminocarbonyl]butoxy}-3,4-dihydrocarbostyril(78346-07-3)
• EPA Substance Registry System: 6-{4-[N-cyclohexylmethyl-N-(3-hydroxypropyl)aminocarbonyl]butoxy}-3,4-dihydrocarbostyril(78346-07-3)

Safety Data

• Hazardous Substances Data: 78346-07-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 58899-20-0 6-(4-carboxybutoxy)-3,4-dihydrocarbostyril 
• 78191-64-7 (N-cyclohexyl N-methylamino)-3 propanol-1 
• 543-27-1 isobutyl chloroformate 
• 54197-66-9 3,4-dihydro-6-hydroxy-2(1H)-quinolinone 
• 78346-46-0 N-(3-hydroxypropyl)-N-(5-chlorovaleryl)-N-cyclohexylemethylamine 
• 584-08-7 potassium carbonate 

Relevant articles and documents

Carbostyril derivatives

Novel carbostyril derivative and its salt represented by the general formula (1), STR1 wherein R1 is a hydrogen atom, a lower alkyl group, a lower alkenyl group or a phenyl-lower alkyl group; R2 is a hydrogen atom, a lower alkyl group or a group of the formula STR2 wherein A is a lower alkylene group; R3 is a lower alkyl group, a hydroxy lower alkyl group, a lower alkoxy-lower alkyl group, a lower alkanoyloxy-lower alkyl group or a benzoyloxy-lower alkyl group; and R4 is a C3-10 -cycloalkyl group which may have at least one hydroxyl group as the substituent(s) in the cycloalkyl ring, a C3-10 -cycloalkyl-lower alkyl group, a phenyl group, a phenyl-lower alkyl group which may have at least one lower alkoxy group as the substituent(s) in the phenyl ring, a lower alkyl group which may have at least one hydroxyl group as the substituent(s), a heterocyclic ring residue or a lower alkyl group having one heterocyclic ring residue as the substituent; further, R3, R4 and the adjacent nitrogen atom, as well as with or without another nitrogen atom, may form a group of the formula STR3 (wherein R5 is a phenyl group, a C3-10 -cycloalkyl group or a phenyl-lower alkyl group; and B is a methine group or a nitrogen atom); the carbon-carbon bond between the 3- and 4-positions in the carbostyril skeleton is a single or double bond; the substituted position of the group of the formula STR4 is any one of 5-, 6-, 7- or 8-position in the carbostyril skeleton; when the group of the formula STR5 is substituted at 5-, 6-, 7- or 8-position in the carbostyril skeleton, then R2 is a hydrogen atom or a lower alkyl group; alternatively, when R2 is a group of the formula STR6 then 5-, 6-, 7- and 8-positions in the carbostyril skeleton are hydrogen atoms and are not substituted with groups of the formula STR7 and when R3 is a lower alkyl group, then R4 should be neither of a C3-10 -cycloalkyl group, a C3-10 -cycloalkyl-lower alkyl group nor a lower alkyl group, having effects for preventing and treating thrombosis and embolism.