78444-81-2

Basic information

• Product Name: 2-tert-butoxycarbonylamino-6-(2-chloro-benzyloxycarbonylamino)-hexanoic acid methyl ester
• CAS NO: 78444-81-2
• Molecular Weight: 428.913
• Mol File: 78444-81-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-tert-butoxycarbonylamino-6-(2-chloro-benzyloxycarbonylamino)-hexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butoxycarbonylamino-6-(2-chloro-benzyloxycarbonylamino)-hexanoic acid methyl ester(78444-81-2)
• EPA Substance Registry System: 2-tert-butoxycarbonylamino-6-(2-chloro-benzyloxycarbonylamino)-hexanoic acid methyl ester(78444-81-2)

Safety Data

• Hazardous Substances Data: 78444-81-2(Hazardous Substances Data)

Upstream product

• 57096-11-4 N6-[[(2-Chlorophenyl)methoxy]carbonyl]-N2-[t-butyloxycarbonyl]-D-lysine 
• 74-88-4 methyl iodide 

Downstream Products

• 445292-08-0 4-acetoxy-5-tert-butoxycarbonylamino-9-(2-chloro-benzyloxycarbonylamino)-non-2-enoic acid tert-butyl ester 
• 359428-54-9 acetic acid 1-[1-tert-butoxycarbonylamino-5-(2-chloro-benzyloxycarbonylamino)-pentyl]-allyl ester 
• 445292-07-9 ((5R,6R)-5-tert-Butoxycarbonylamino-6-hydroxy-oct-7-enyl)-carbamic acid 2-chloro-benzyl ester 
• 445292-06-8 (5-tert-butoxycarbonylamino-6-oxo-hexyl)-carbamic acid 2-chloro-benzyl ester 

Relevant articles and documents

Synthesis and evaluation of pseudopeptide analogues of a specific CXCR4 inhibitor, T140: the insertion of an (E)-alkene dipeptide isostere into the betaII'-turn moiety.

A 14-residue peptide, T140, strongly inhibits the T-cell line-tropic HIV-1 (X4-HIV-1) infection, since this peptide functions as a specific antagonist against a chemokine receptor, CXCR4. T140 takes an antiparallel beta-sheet structure with a type II' bet