78641-69-7Relevant articles and documents
3,5-DINITRO-1-(4-NITROPHENYL)-4-PYRIDONE, A NOVEL AND CONVENIENT PROTECTING REAGENT FOR PRIMARY AMINES.
Matsumura,Kobayashi,Nishikawa,Ariga,Tohda,Kawashima
, p. 1961 - 1965 (2007/10/02)
Crystalline derivatives of the following L-amino acids modified by 2,5-dinitro-4-pyridone have been prepared: glycine, alanine, valine, leucine, isoleucine, phenylalanine, serine, threonine, tyrosine, aspartic acid, asparagine, glutamic acid, glutamine, tryptophan, histidine, arginine, methionine and lysine. The modified L-amino acids (DNPY-L-amino acids) could be purified by recrystallization and were characterized by **1H-NMR, IR and UV spectral data. The molar rotation of the DNPY-L-amino acids varied from 2 to 100 times those of the parent amino acids. The effectiveness of 3,5-dinitro-1-(4-nitrophenyl)-4-pyridone as an amino-protecting reagent of L-amino acids is described.