78842-52-1Relevant articles and documents
Method for preparing cyclocitral by micro-structural reactors
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Paragraph 0052; 0053, (2017/02/09)
The invention discloses a method for preparing cyclocitral by micro-structural reactors. The method comprises steps as follows: a liquid raw material citral and organic amine in a mole ratio being 1: (0.8-1.5) are simultaneously pumped into a tubular reactor or one micro-structural reactor for an amination reaction, the reaction temperature of the reactor is controlled in a range of 10-20 DEG C, a flow velocity of a reaction liquid is controlled, the reaction liquid is enabled to totally stay in the reactor for 0.1-25 min, and obtained aldimine and concentrated sulfuric acid are injected into another micro-structural reactor and subjected to a ring closing reaction; a reaction product is neutralized by a sodium hydroxide solution and is subjected to acidic hydrolysis, liquid separation, reduced pressure distillation and drying, and a pale yellow oily product, namely, cyclocitral, is obtained. According to the method, the reaction time is short, the reaction temperature is accurate and controllable, and product selectivity and yield are high. The method adopts simple steps, and is convenient to operate and high in practicability.
