79-85-6

Basic information

• Product Name: (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino- 6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12 -trione
• Synonyms: (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino- 6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12 -trione;4-EPI-TETRACYCLINE;Quatrimycin
• CAS NO: 79-85-6
• Molecular Formula: C22H24N2O8
• Molecular Weight: 444.4346
• Mol File: 79-85-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 170-171 °C (decomp)
• Boiling Point: 682.8 °C at 760 mmHg
• Flash Point: 366.7 °C
• Appearance: /
• Density: 1.64 g/cm³
• Vapor Pressure: 1.41E-19mmHg at 25°C
• Refractive Index: 1.74
• PKA: pKa 4.8 (MeOH/H2O (1:1)t=30±2 ) (Uncertain);8.0 (MeOH/H2O (1:1)t=30±2 ) (Uncertain);9.3(MeOH/H2O (1:1)t=30±2 ) (Uncertain)
• CAS DataBase Reference: (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino- 6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12 -trione(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino- 6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12 -trione(79-85-6)
• EPA Substance Registry System: (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino- 6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12 -trione(79-85-6)

Safety Data

• Hazardous Substances Data: 79-85-6(Hazardous Substances Data)

Usage

Description

(2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione is a complex organic compound with a tetracycline structure. It features multiple functional groups, including amino, hydroxyl, and methylidene groups, as well as a tetrahydroxy and tetrahydrotetracene structure, and a trione functional group. (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12 -trione is likely to possess antibiotic properties due to its tetracycline structure, which is known for its antibacterial activity. The presence of multiple hydroxyl groups and the trione moiety may also endow the compound with additional biological activities, making it a potentially interesting candidate for further study in pharmaceutical and medical research.

Uses

Used in Pharmaceutical Industry:
(2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione is used as an antibiotic agent for its potential antibacterial properties due to its tetracycline structure. (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12 -trione may be effective against a range of bacterial infections, offering an alternative or complementary treatment option in the fight against antibiotic-resistant bacteria.
Used in Medical Research:
In the field of medical research, (2Z,4R,4aS,5aS,6S,12aS)-2-(amino-hydroxy-methylidene)-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione can be employed as a subject for studying its potential biological activities and interactions with biological systems. The presence of multiple hydroxyl groups and the trione moiety may provide insights into the compound's ability to target specific cellular pathways or mechanisms, potentially leading to the development of new therapeutic agents or strategies for treating various diseases and conditions.

InChI:InChI=1/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25-26,30-32H,7,23H2,1-3H3/b20-14-/t9-,10-,15+,21+,22-/m0/s1

Downstream Products

• 319426-63-6 tetracycline galactoside conjugate