79023-06-6

Basic information

• Product Name: 5-(4-methoxyphenyl)pentanoic acid ethyl ester
• Synonyms: 5-(4-methoxyphenyl)pentanoic acid ethyl ester
• CAS NO: 79023-06-6
• Molecular Weight: 236.311
• Mol File: 79023-06-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 5-(4-methoxyphenyl)pentanoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-methoxyphenyl)pentanoic acid ethyl ester(79023-06-6)
• EPA Substance Registry System: 5-(4-methoxyphenyl)pentanoic acid ethyl ester(79023-06-6)

Safety Data

• Hazardous Substances Data: 79023-06-6(Hazardous Substances Data)

Upstream product

• 1187780-60-4 ethyl (Z)-5-(4-methoxyphenyl)pent-4-enoate 
• 15823-04-8 methyl 3-(4-methoxyphenyl)propionate 
• 1929-29-9 3-(4-methoxyphenyl)propanoic acid 
• 943-89-5 (E)-3-(4-methoxyphenyl)acrylic acid 
• 22767-72-2 ethyl 3-(4-methoxyphenyl)propanoate 
• 344360-08-3 5-(4-methoxyphenyl)pent-2-enoic acid ethyl ester 
• 24393-56-4 ethyl p-methoxycinnamate 
• 20401-88-1 3-(4-methoxyphenyl)propional 
• 123-11-5 4-methoxy-benzaldehyde 
• 5406-18-8 3-(p-methoxyphenyl)-1-propanol 
• 105-13-5 4-Methoxybenzyl alcohol 
• 14660-52-7 ethyl 5-bromovalerate 
• 696-62-8 para-iodoanisole 
• 15542-26-4 (2E,4E)-ethyl 5-(4'-methoxyphenyl)penta-2,4-dienoate 

Downstream Products

• 87077-57-4 6-(4-methoxy-phenyl)-2-methyl-hexan-2-ol 
• 854401-87-9 1,10-bis-(4-methoxy-phenyl)-decane-5,6-diol 
• 14374-54-0 5-(4-methoxyphenyl)pentan-1-ol 
• 4280-60-8 1,10-bis(4-methoxyphenyl)decane 
• 14469-84-2 1-(para-anisyl)-5-bromopentane 
• 127047-17-0 5-(4-methoxyphenyl)pentan-1-al 
• 61875-52-3 5-(4-methoxy-phenyl)-valeryl chloride 
• 1071001-50-7 1,1,1,2,2-pentafluoro-7-(4-methoxyphenyl)heptan-3-one 
• 7508-04-5 5-(4-methoxyphenyl)pentanoic acid 

Relevant articles and documents

Copper-catalyzed sp3-sp3 cross-coupling of turbo grignards with benzyl halides

The aromatic ring in benzyl halides and sulfonates imparts unique reactivity at the benzylic carbon atom. Photoredox sp3-sp3 cross-coupling proved ineffective for coupling p-methoxybenzyl chloride (PMBCl), leading to a new strategy for the sp3-sp3 cross-coupling of benzyl halides and sulfonates. This strategy involved LiCl-accelerated synthesis of a Grignard reagent followed by a copper-catalyzed cross-coupling. The conditions worked well for PMBCl due to its exceptional reactivity but other benzyl bromides or sulfonates reacted poorly.

Synthesis, in vitro and in silico evaluation of diaryl heptanones as potential 5LOX enzyme inhibitors

A new series of diaryl heptanones (12a-q) were synthesized and their structures were confirmed by its 1H, 13C NMR and Mass spectral data. These analogs were evaluated for their anti-oxidant activity and potential to inhibit 5-lipoxygenase. Compounds 12k and 12o showed potent in vitro 5-lipoxygenase enzyme inhibitory activity with IC50 values of 22.2, 21.5 μM, which are comparable to curcumin (24.4 μM). Further they also have shown significant antioxidant activity. Molecular docking studies clearly showed correlation between binding energy and potency of these compounds.

New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2

Group VIA calcium-independent phospholipase A2 (GVIA iPLA 2) has recently emerged as an important pharmaceutical target. Selective and potent GVIA iPLA2 inhibitors can be used to study its role in various neurological diso