79352-66-2

Basic information

• Product Name: 4-(benzyloxy)-2-bromophenol
• Synonyms: 4-(benzyloxy)-2-bromophenol
• CAS NO: 79352-66-2
• Molecular Formula: C₁₃H₁₁BrO₂
• Molecular Weight: 279.12924
• EINECS: -0
• Mol File: 79352-66-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 72-73 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 370.0±27.0 °C(Predicted)
• Appearance: /
• Density: 1.478±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.79±0.20(Predicted)
• CAS DataBase Reference: 4-(benzyloxy)-2-bromophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxy)-2-bromophenol(79352-66-2)
• EPA Substance Registry System: 4-(benzyloxy)-2-bromophenol(79352-66-2)

Safety Data

• Hazardous Substances Data: 79352-66-2(Hazardous Substances Data)

Usage

Description

4-(Benzyloxy)-2-bromophenol is an organic compound characterized by the presence of a benzyloxy group attached to the 4-position and a bromine atom at the 2-position of a phenol molecule. This unique structure endows it with specific chemical properties that make it a valuable intermediate in the synthesis of various pharmaceutical compounds.

Uses

Used in Pharmaceutical Synthesis:
4-(Benzyloxy)-2-bromophenol is used as an intermediate in the synthesis of (S)-4-Hydroxy Penbutolol Hydrochloride (H948945), a hydroxylated metabolite of Penbutolol (P220500). This intermediate plays a crucial role in the production of pharmaceuticals, contributing to the development of medications with potential therapeutic benefits.

Upstream product

• 103-16-2 4-Benzyloxyphenol 
• 121767-81-5 4-Benzyloxy-2-bromo-1-(2-chloro-ethoxy)-benzene 

Downstream Products

• 299917-34-3 5-Benzyloxy-2-methoxymethyloxy-1-bromobenzene 
• 328919-60-4 2-(4-Benzyloxy-2-bromo-phenoxy)-2-methyl-propionic acid ethyl ester 
• 358388-32-6 5-Benzyloxy-2-ethoxybrombenzene 
• 936711-76-1 (4-benzyloxy-2-bromo-phenoxy)-tert-butyl-dimethyl-silane 
• 1372147-55-1 4-[4-(benzyloxy)-2-bromophenoxymethyl]pyridine 
• 1426068-31-6 (4-benzyloxy-2-bromophenyl)-N-cyclohexylcarbamate 
• 79352-67-3 1-benzyloxy-4-methoxy-9,10-anthraquinone 

Relevant articles and documents

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Novel imidazotrizinones of general formula (I), a method for the production and the pharmaceutical use thereof are disclosed.