80312-74-9

Basic information

• Product Name: Carbamic acid, [(2S)-2-amino-3-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(2S)-2-amino-3-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI);(2S)-3-(Boc-amino)-2-amino-1-propanol
• CAS NO: 80312-74-9
• Molecular Formula: C8H18N2O3
• Molecular Weight: 190.24012
• Product Categories: N-BOC
• Mol File: 80312-74-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 350.2±32.0 °C(Predicted)
• Appearance: /
• Density: 1.090±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 12.31±0.46(Predicted)
• CAS DataBase Reference: Carbamic acid, [(2S)-2-amino-3-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(2S)-2-amino-3-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)(80312-74-9)
• EPA Substance Registry System: Carbamic acid, [(2S)-2-amino-3-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)(80312-74-9)

Safety Data

• Hazardous Substances Data: 80312-74-9(Hazardous Substances Data)

Upstream product

• 159002-15-0 (S)-2-(benzyloxycarbonylamino)-3-(tert-butoxycarbonylamino)propionoic acid 
• 74536-29-1 (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoic acid 
• 58457-98-0 methyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-[(tert-butoxycarbonyl)amino]propanoate 
• 16947-84-5 N-[(benzyloxy)carbonyl]-3-[(tert-butoxycarbonyl)amino]-L-alanine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 199005-69-1 (S)-N²-benzyloxycarbonyl-N³-tert-butyloxycarbonyl-2,3-diaminopropan-1-ol 

Downstream Products

• 199005-71-5 {(S)-1-[(S)-1-((S)-2-tert-Butoxycarbonylamino-1-formyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester 

Relevant articles and documents

METALLO-BETA-LACTAMASE INHIBITORS

The present invention relates to compounds of formula I that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

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