805-26-5 Usage
Description
Estriol 16,17-diacetate is a diacetate derivative of Estriol, an estrogenic metabolite that is considerably less potent than the hormone Estradiol. It is characterized by the presence of two acetyl groups attached to the 16th and 17th carbon atoms of the Estriol molecule, which may influence its chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
Estriol 16,17-diacetate is used as a pharmaceutical agent for its estrogenic properties, albeit less potent than Estradiol. It may be utilized in hormone replacement therapies or other treatments where a weaker estrogenic effect is desired.
Used in Research Applications:
In scientific research, Estriol 16,17-diacetate can be used as a research tool to study the effects of estrogenic compounds on various biological processes. Its less potent nature compared to Estradiol may provide a controlled means to investigate the influence of estrogens in a more nuanced manner.
Used in Hormone Regulation:
Estriol 16,17-diacetate may be employed in the development of treatments aimed at regulating hormone levels, particularly in conditions where a milder estrogenic effect is preferable to avoid potential side effects associated with more potent estrogens.
Check Digit Verification of cas no
The CAS Registry Mumber 805-26-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,0 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 805-26:
(5*8)+(4*0)+(3*5)+(2*2)+(1*6)=65
65 % 10 = 5
So 805-26-5 is a valid CAS Registry Number.
InChI:InChI=1/C22H28O5/c1-12(23)26-20-11-19-18-6-4-14-10-15(25)5-7-16(14)17(18)8-9-22(19,3)21(20)27-13(2)24/h5,7,10,17-21,25H,4,6,8-9,11H2,1-3H3/t17-,18-,19+,20-,21+,22+/m1/s1
805-26-5Relevant articles and documents
Palladium-Catalyzed Ortho-Arylation of Carbamate-Protected Estrogens
Bedford, Robin B.,Brenner, Peter B.,Durrant, Steven J.,Gallagher, Timothy,Méndez-Gálvez, Carolina,Montgomery, Michelle
, p. 3473 - 3478 (2016)
The palladium-catalyzed ortho-arylation of diethyl carbamate-protected estrone and estriol with aryl iodides gives the 2-arylated analogues. Subsequent removal of the carbamate directing group furnishes 2-arylated estrone, estradiol, or estriol depending on the method used.
An efficient method for selective acetylation of alcoholic hydroxyl groups
Nagao,Fujita,Kohno,Yagi
, p. 3202 - 3207 (2007/10/02)
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Hydrogen sulfates of natural estrogens.
Fex,Lundvall,Olsson
, p. 254 - 264 (2007/10/06)
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