8051-88-5

Basic information

• Product Name: OLEIC ACID-1-13C
• Synonyms: Oleic Acid-Cyclodextrin Complex;(Z)-9-Octadecenoate;Oleic acid anion;Caswell no. 899;Einecs 232-306-7;Epa pesticide chemical code 079014;(Z)-9-OCTADECANOIC ACID;(Z)-9-OCTADECENOIC ACID
• CAS NO: 8051-88-5
• Molecular Formula: C18H34O2
• Molecular Weight: 283.47
• EINECS: 204-007-1
• Product Categories: Unsaturated Fatty Acids 13C & 2H
• Mol File: 8051-88-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 13-14 °C(lit.)
• Boiling Point: 194-195 °C1.2 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /powder
• Density: 0.893 g/mL at 25 °C
• Vapor Pressure: 1 mm Hg ( 176 °C)
• Refractive Index: n20/D 1.4595(lit.)
• Storage Temp.: 2-8°C
• Solubility: H2O: 50 mg/mL, may be clear to slightly hazy
• CAS DataBase Reference: OLEIC ACID-1-13C(CAS DataBase Reference)
• NIST Chemistry Reference: OLEIC ACID-1-13C(8051-88-5)
• EPA Substance Registry System: OLEIC ACID-1-13C(8051-88-5)

Safety Data

• Hazard Codes: Xi
• Statements: 38-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: RG2275000
• F: 8-10-23
• Hazardous Substances Data: 8051-88-5(Hazardous Substances Data)

Usage

Description

OLEIC ACID-1-13C is a stable isotope-labeled fatty acid, specifically an octadecenoate, where one of the carbon atoms is replaced with the non-radioactive isotope carbon-13. This modification allows for the tracking and analysis of metabolic pathways and biochemical processes involving oleic acid in various applications.

Uses

Used in Biomedical Research:
OLEIC ACID-1-13C is used as a tracer compound for investigating the metabolic fate and distribution of oleic acid in biological systems. Its use enables researchers to study the incorporation of oleic acid into lipids, its conversion to other bioactive molecules, and its role in cellular processes.
Used in Cell Biology Applications:
OLEIC ACID-1-13C is used as a tool to prepare free fatty acid (FFA) mixtures for cell treatment. This allows researchers to study the effects of oleic acid on cellular functions, such as its influence on the expression of solute carrier family 2 member 4 (SLC2A4)/GLUT4 in L6 muscle cells, which are involved in glucose transport and metabolism.
Used in Transcriptional Regulation Studies:
OLEIC ACID-1-13C is utilized as a potential transcriptional regulator to investigate its effects on gene expression and the underlying mechanisms. This can provide insights into the role of oleic acid in the regulation of cellular processes and its potential as a therapeutic agent.
Used in Hepatology Research:
OLEIC ACID-1-13C is employed in the preparation of fatting media for the induction of in vitro steatosis in primary human hepatocytes. This application aids in the study of the development of fatty liver disease and the role of oleic acid in hepatic lipid metabolism and steatosis progression.
Used in Pharmaceutical Development:
OLEIC ACID-1-13C is used in the development of drug delivery systems, as it can be incorporated into various formulations to enhance the solubility, bioavailability, and targeted delivery of therapeutic agents.
Used in Nutritional Studies:
OLEIC ACID-1-13C is utilized in nutritional research to study the absorption, distribution, metabolism, and excretion of oleic acid in the body, providing valuable information on its nutritional properties and potential health benefits.
Used in Analytical Chemistry:
OLEIC ACID-1-13C serves as an internal standard in analytical methods, such as mass spectrometry and nuclear magnetic resonance spectroscopy, for the accurate quantification and identification of oleic acid and its metabolites in complex biological samples.