80585-43-9Relevant articles and documents
SELF-COMPLEMENTARY TETRADEOXYRIBONUCLEOSIDE TRIPHOSPHATES. CONVENIENT CHEMICAL PREPARATION AND SPECTROSCOPIC STUDIES IN SOLUTION
Matsuzaki, Jun-ichi,Hotoda, Hitoshi,Sekine, Mitsuo,Hata, Tsujiaki,Higuchi, Shigesada,et al.
, p. 501 - 514 (2007/10/02)
Eight kinds of self-complementary tetradeoxyribonucleoside triphosphates were prepared by a simplified method which enabled us to omit purification of synthetic intermediates and provided the tetramers very rapidly and conveniently.The tetramers were characterized by enzyme assay and their conformations were studied by the use of UV and CD spectroscopic methods under various conditions.The detailed analysis of the CD spectra suggested that conformation of the tetramer duplexes was dependent on the sequence.
PHOSPHOTRIESTER APPROACH TO OLIGOTHYMIDYLATE SYNTHESIS UTILIZING A SIMPLE THYMIDINE UNIT AND A NEW TYPE OF CONDENSING AGENT
Sekine, Mitsuo,Matsuzaki, Jun-ichi,Hata, Tsujiaki
, p. 3209 - 3212 (2007/10/02)
DMTrTp(SPh)2 was proposed as a simplest "nucleotide unit" for the synthesis of olygothymidylates.One phenylthio group was removed selectively and rapidly from dithiol-esters by 1M pyridinium hypophosphonate.Two kinds of arenedisulfonyl chlorides were newl