80909-79-1Relevant articles and documents
Practical corey-chaykovsky epoxidation: Scope and limitation
Yu, Hao,Deng, Xiaobing,Cao, Shengli,Xu, Jiaxi
, p. 509 - 514 (2011)
Corey-Chaykovsky epoxidation is one of the versatile methods for synthesis of structurally diverse oxiranes. The extension of simplified Corey-Chaykovsky epoxidation has been investigated. Ketones and aromatic aldehydes were epoxidized in satisfactory to excellent yields with trimethylsulfonium iodide as an ylide precursor and crushed potassium hydroxide as a base in tertiary butanol.The scope and limitation of the simplified procedure were examined. The results revealed that the procedure is applicable to the epoxidation of ketones and aromatic aldehydes.