80971-82-0

Basic information

• Product Name: BOC-TYR(AC)-OH
• Synonyms: BOC-TYR(AC)-OH;BOC-TYROSINE(AC)-OH;BOC-O-ACETYL-L-TYROSINE;BOC-L-TYROSINE(ACETYL);N-ALPHA-T-BUTOXYCARBONYL-O-ACETYL-L-TYROSINE;NALPHA-tert-Butoxycarbonyl-O-acetyl-L-tyrosine;Boc-L-Tyr(Ac)-OH;Boc-O-acetyl-L-tyrosine99%
• CAS NO: 80971-82-0
• Molecular Formula: C₁₆H₂₁NO₆
• Molecular Weight: 323.34
• Mol File: 80971-82-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: BOC-TYR(AC)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-TYR(AC)-OH(80971-82-0)
• EPA Substance Registry System: BOC-TYR(AC)-OH(80971-82-0)

Safety Data

• Hazardous Substances Data: 80971-82-0(Hazardous Substances Data)

Usage

Description

BOC-TYR(AC)-OH is a chemical compound utilized in peptide synthesis, featuring a protected tyrosine amino acid with an acetyl group on its side chain. BOC-TYR(AC)-OH acts as a fundamental building block in the solid-phase peptide synthesis process, enabling the assembly of specific peptide sequences through the combination with other amino acids. The BOC (tert-butyloxycarbonyl) protecting group on the amino group and the acetyl group on the side chain are strategically placed to temporarily block reactive sites on the tyrosine molecule, facilitating controlled manipulation and deprotection during peptide assembly. BOC-TYR(AC)-OH is a crucial reagent for crafting custom peptides, serving various applications in research, drug development, and other areas within biochemistry and molecular biology.

Uses

Used in Peptide Synthesis:
BOC-TYR(AC)-OH is used as a building block in the solid-phase peptide synthesis process for the creation of specific peptide sequences. Its protecting groups allow for controlled manipulation and deprotection during peptide assembly, ensuring the accurate formation of desired peptide structures.
Used in Research and Development:
BOC-TYR(AC)-OH is used as a reagent in the development of custom peptides for research purposes, enabling scientists to explore the properties and potential applications of novel peptide sequences.
Used in Drug Development:
In the pharmaceutical industry, BOC-TYR(AC)-OH is utilized for the synthesis of peptides with therapeutic potential, contributing to the discovery and development of new drugs and treatments.
Used in Biochemistry and Molecular Biology:
BOC-TYR(AC)-OH is employed in various applications within biochemistry and molecular biology, such as the study of protein structure and function, as well as the development of diagnostic tools and therapeutic agents based on peptide sequences.

Upstream product

• 3978-80-1 Boc-Tyr-OH 
• 108-24-7 acetic anhydride 

Downstream Products

• 291313-44-5 (S)-N-[(S)-1-benzyl-2-hydroxyethyl]-3-(4-acetoxyphenyl)-2-[N-(tert.butoxycarbonyl)amino]propionamide 
• 18938-60-8 (S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoate 
• 1188307-55-2 Boc-Tyr(Ac)-Gly-Gly-OAll 
• 142978-59-4 Acetic acid 4-((S)-2-{4-[3-(3-amino-propylamino)-propylamino]-butylcarbamoyl}-2-butyrylamino-ethyl)-phenyl ester 
• 474070-52-5 N-butyryl-O-acetyl-L-tyrosine p-nitrophenyl ester 
• 80971-85-3 (S)-2-{(S)-2-[2-({1-[(S)-3-(4-Acetoxy-phenyl)-2-amino-propionylamino]-cyclopropanecarbonyl}-amino)-acetylamino]-3-phenyl-propionylamino}-4-methyl-pentanoic acid 
• 80971-87-5 1-(L-tyrosyl)aminocyclopropane-1-carbonylglycyl-L-phenylalanyl-L-leucine 
• 291313-54-7 (S)-2-[(S)-2-(4-acetoxyphenyl)-1-[N-(tert-butoxycarbonyl)amino]ethyl]-4-benzyl-2-oxazoline 
• 210707-19-0 (S)-4-benzyl-2-[(S)-1-[N-(tert-butoxycarbonyl)amino]-2-(4-hydroxyphenyl)ethyl]-2-oxazoline 

Relevant articles and documents

Synergistic Photobactericidal Activity Based on Ultraviolet-A Irradiation and Ferulic Acid Derivatives

Ultraviolet-A (UV-A)-mediated bactericidal activity was enhanced by combined treatment with trans-ferulic acid (trans-FA, compound 1) or its derivatives. Derivative compounds 4 and 10 contain a phenyl group or an l-tyrosine HCl tert-butyl ester, respectiv

New oxidative transformations of phenolic and indolic oxazolines: An avenue to useful azaspirocyclic building-blocks

The oxidative cyclization of a phenolic amide to a spirolactam has long been regarded as an 'impossible' reaction, because exposure of the substrates to a variety of oxidants results in formation of spirolactones with consequent loss of the amine segment. We recently communicated that this heretofore unknown transformation may be achieved by oxidation of oxazoline analogues of phenolic and indolic amides. Herein, we provide full details of our work.

Synthesis of glutamate receptor antagonist philanthotoxin-433 (PhTX-433) and its analogs

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