81000-39-7

Basic information

• Product Name: Benzenepropanethioic acid, a-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-
• CAS NO: 81000-39-7
• Molecular Formula: C14H19NO3S
• Molecular Weight: 281.376
• Mol File: 81000-39-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzenepropanethioic acid, a-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanethioic acid, a-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-(81000-39-7)
• EPA Substance Registry System: Benzenepropanethioic acid, a-[[(1,1-dimethylethoxy)carbonyl]amino]-, (S)-(81000-39-7)

Safety Data

• Hazardous Substances Data: 81000-39-7(Hazardous Substances Data)

Upstream product

• 1274754-60-7 S-(tert-butyl) (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanethioate 
• 1330059-29-4 N-tert-butoxycarbonyl-L-phenylalanine 9-fluorenylmethyl thioester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 119153-87-6 (C₅H₉O₂)C₉H₉NO(O)(CO₂C₂H₅) 

Downstream Products

• 929681-24-3 C₂₂H₂₅NO₄S 
• 78605-47-7 N-tert-butoxycarbonyl-L-phenylalanyl-L-alanine ethyl ester 
• 1187922-70-8 (S)-tert-butyl (1-(4-methylphenylsulfonamido)-1-oxo-3-phenylpropan-2-yl)carbamate 
• 97885-48-8 N-(1,1-dimethylethoxycarbonyl)-L-phenylalanine N-(4-nitrophenyl)amide 
• 95364-14-0 (S)-2-tert-butoxycarbonylamino-3-phenylthiopropionic acid S-benzyl ester 
• 870533-26-9 (S)-tert-butyl (1-((4-methoxyphenyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate 
• 15136-29-5 (S)-methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanamido)propanoate 
• 2754-02-1 N-(N-(1,1-dimethylethoxycarbonyl)-L-phenylalanyl)-L-valine methyl ester 
• 876133-31-2 methyl N'-(tert-butoxycarbonyl)-L-phenylalanyl-D-valinate 
• 83522-39-8 N^α-(tert-butoxycarbonyl)-L-phenylalanyl-L-tryptophan methyl ester 
• 66076-54-8 N-tert-butyloxycarbonyl-L-phenylalanine-L-tyrosine methyl ester 
• 15215-74-4 methyl (tert-butoxycarbonyl)-L-phenylalanyl-L-phenylalaninate 
• 13122-89-9 (S)-methyl 2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-3-phenylpropanoate 
• 1362688-99-0 C₁₇H₂₄BrNO₃S 

Relevant articles and documents

α-Methylphenacyl thioesters as convenient thioacid precursors

α-Methylphenacyl (Mpa) thioesters are described as precursors of thioacids. Mpa thioesters are accessible via the condensation of carboxylic acids and phenacyl thiol, which is easily prepared without column chromatography. The Mpa thioesters are selectively deprotected by reduction with zinc dust in the presence of conventional thioacid protecting groups. In addition, the Mpa group exhibits orthogonal reactivity to the Boc group. These features are expected to facilitate the preparation of complex thioacids, including those in peptides.

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