81115-79-9

Basic information

• Product Name: N-[2-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylmethyl)-phenyl]-acetamide
• CAS NO: 81115-79-9
• Molecular Weight: 335.406
• Mol File: 81115-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylmethyl)-phenyl]-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylmethyl)-phenyl]-acetamide(81115-79-9)
• EPA Substance Registry System: N-[2-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylmethyl)-phenyl]-acetamide(81115-79-9)

Safety Data

• Hazardous Substances Data: 81115-79-9(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 81115-76-6 1-phenyl-2,3-dimethyl-4-(NN-dimethylaminomethyl)-pyrazol-5-one 
• 108-24-7 acetic anhydride 
• 58532-88-0 4-(2-amino-benzyl)-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one 

Relevant articles and documents

A General and Practicable Synthesis of Polycyclic Heteroaromatic Compounds. Part 4. A Rationale for the Mechanism of the Synthesis

Studies on aspects of the mechanism of our general synthesis of polycyclic heteroaromatic compounds suggest that the reaction sequence outlined in Scheme 2 is followed.Under the conditions of our synthesis, the ortho-rearrangement (8) --> (9) is preferred to the para-rearrangement which is known to occur in acid conditions.Aniline Mannich bases (29) are converted to benzacridines (30) in an intermolecular reaction.The synthesis appears to be restricted to substrates where the putative intermediate (9) is not part of an amide group.In the course of these studies effective syntheses of the tricyclic compounds (24) and (25) have been discovered.