812788-12-8

Basic information

• Product Name: 2,5-Morpholinedione,4-methyl-3,6-bis(1-methylethyl)-,(3S,6R)-(9CI)
• Synonyms: 2,5-Morpholinedione,4-methyl-3,6-bis(1-methylethyl)-,(3S,6R)-(9CI)
• CAS NO: 812788-12-8
• Molecular Formula: C11H19NO3
• Molecular Weight: 0
• Product Categories: METHYL
• Mol File: 812788-12-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Morpholinedione,4-methyl-3,6-bis(1-methylethyl)-,(3S,6R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Morpholinedione,4-methyl-3,6-bis(1-methylethyl)-,(3S,6R)-(9CI)(812788-12-8)
• EPA Substance Registry System: 2,5-Morpholinedione,4-methyl-3,6-bis(1-methylethyl)-,(3S,6R)-(9CI)(812788-12-8)

Safety Data

• Hazardous Substances Data: 812788-12-8(Hazardous Substances Data)

Usage

Also known as

morpholine-2,5-dione

Type of compound

cyclic urea derivative

Common use

intermediate in the synthesis of pharmaceuticals and organic compounds

Potential applications

medicine and agriculture

Spatial arrangement of atoms

3S,6R configuration

Importance of spatial arrangement

can have implications for biological activity and chemical reactivity

Additional research needed

to fully understand properties and potential uses

Upstream product

• 2480-23-1 N-methylvaline 
• 917-13-5 enniatin B 
• 812788-38-8 (S)-3-Methyl-2-methylamino-butyric acid (R)-1-carboxy-2-methyl-propyl ester 
• 17407-56-6 (R)-2-Hydroxy-3-methylbutyric acid 
• 18668-12-7 N-Benzyloxycarbonyl-N-methyl-L-Val-D-α-hydroxy-isovaleriansaeure 
• 42417-65-2 Z-MeVal-OH 

Relevant articles and documents

Induced production of depsipeptides by co-culturing fusarium tricinctum and fusarium begoniae

A co-culture of Fusarium tricinctum and Fusarium begoniae induced the production of two new linear depsipeptides, subenniatins A and B (1-2), which were not detected when either of the two fungi was cultured alone. The structures of the new compounds were unambiguously determined by analysis of 1D, 2D NMR, and mass spectra, as well as by chemical transformation. Complex NMR spectra were observed for compounds 1 and 2, which were attributed to the presence of rotamers as revealed by 1D NOE and ROESY measurements. Structurally, compounds 1 and 2 are biogenetic building blocks of the cytotoxic enniatins B, B1, A1, and A, which are the major metabolites of F. tricinctum when this fungus is cultured alone. Compounds 1 and 2 were found to be inactive in cytotoxic and antibacterial assays.