813-56-9 Usage
Description
MALONIC-D2 ACID-D2, also known as Malonic Acid-d4, is an isotope-labeled analog of Malonic Acid. It is a small bioactive molecule that can be used in various chemical reactions. As a classic example of a competitive inhibitor, it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. MALONIC-D2 ACID-D2 is characterized by its fine powder chemical properties.
Uses
Used in Chemical Reactions:
MALONIC-D2 ACID-D2 is used as a reagent in various chemical reactions due to its bioactive properties. Its isotope-labeled nature allows for tracking and analysis of reaction mechanisms and pathways.
Used in Enzyme Inhibition Studies:
In the field of biochemistry, MALONIC-D2 ACID-D2 is used as a competitive inhibitor for studying the function and inhibition of succinate dehydrogenase (complex II) in the respiratory electron transport chain. This helps researchers understand the enzyme's role in cellular respiration and develop potential therapeutic agents targeting this enzyme.
Used in Pharmaceutical Industry:
MALONIC-D2 ACID-D2 is used as an intermediate in the synthesis of pharmaceutical compounds. Its unique properties make it a valuable building block for developing new drugs and improving existing ones.
Used in Research and Development:
In the research and development sector, MALONIC-D2 ACID-D2 is used as a tool to study metabolic pathways and enzyme mechanisms. Its isotope-labeled nature provides a means to trace and analyze metabolic processes, leading to a better understanding of biological systems and the development of targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 813-56-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,1 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 813-56:
(5*8)+(4*1)+(3*3)+(2*5)+(1*6)=69
69 % 10 = 9
So 813-56-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)/i1D2/hD2
813-56-9Relevant articles and documents
ESTIMATION OF MALONIC ACID AND METHYLMALONIC ACID ENOLIZATION RATE CONSTANTS BY AN ISOTOPIC-EXCHANGE REACTION USING 1H NMR SPECTROSCOPY
Hansen, Eddy W.,Ruoff, Peter
, p. 2641 - 2645 (1988)
In the oscillatory Belousov-Zhabotinsky (BZ) reaction, bromination of the organic substrate is an important component process.Because bromination of the organic substrate in the BZ reaction occurs via an enolization mechanism, which generally is considered to be rate determining, the enolization rate constants are important parameters.In this paper, we erport enolization rate constants of malonic and methylmalonic acid in 1 M sulfuric acid by following with 1H NMR spectroscopy the isotopic substitution of enol-exchangeable hydrogen atoms by deuterium.We find for the first enolization step of malonic acid a rate constant of (1.066+/-0.003)x1E-3 s-1 and for the second enolization step a rate constant value of (4.2+/0.2)x1E-4 s-1.The corresponding value for methylmalonic acid is (5.7+/-0.1)x1E-5 s-1.While earlier literature data for malonic acid are difficult to compare with our present results, the determined enolization rate constant for methylmalonic acid is in excellent agreement with two other experimental determinations performed in 1 M sulfuric acid.When the sulfuric acid activity is taken into account, then methylmalonic acid enolization rates can be extrapolated to other sulfuric acid concentrations.
