81348-81-4

Basic information

• Product Name: Momordioside F1
• Synonyms: (23E)-3β-(β-D-Glucopyranosyloxy)-25-methoxy-5,19-epoxy-5β-cucurbita-6,23-diene;(23E)-5,19-Epoxy-3β-β-D-glucopyranosyloxy-25-methoxy-5β-cucurbita-6,23-diene;Momordicoside F1;Momordioside F1;(3S,5R,8S,9S,10S,13R,14S,17R)-1,3,4,8,10,11,12,13,14,15,16,17-Dodecahydro-17-[(1R)-5-methoxy-1,5-dimethyl-3-hexenyl]-4,4,13,14-tetramethyl-5,9-(epoxymethano)-2H-cyclopenta[a]phenanthren-3-yl beta-D-glucopyranoside
• CAS NO: 81348-81-4
• Molecular Formula: C37H60O8
• Molecular Weight: 632.8675
• Mol File: 81348-81-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 711.4±60.0 °C(Predicted)
• Appearance: /
• Density: 1.20±0.1 g/cm3(Predicted)
• PKA: 12.91±0.70(Predicted)
• CAS DataBase Reference: Momordioside F1(CAS DataBase Reference)
• NIST Chemistry Reference: Momordioside F1(81348-81-4)
• EPA Substance Registry System: Momordioside F1(81348-81-4)

Safety Data

• Hazardous Substances Data: 81348-81-4(Hazardous Substances Data)

Usage

Description

Momordioside F1 is a bioactive chemical compound derived from bitter melon (Momordica charantia), known for its diverse therapeutic properties. It exhibits anti-inflammatory, antioxidant, and anticancer activities, making it a promising candidate for the treatment of various diseases and conditions.

Uses

Used in Pharmaceutical Industry:
Momordioside F1 is used as a therapeutic agent for its anti-inflammatory and antioxidant properties, potentially treating conditions such as diabetes, cardiovascular diseases, and neurodegenerative disorders. Its protective effects against oxidative stress and inflammation contribute to its potential applications in these areas.
Used in Cancer Treatment:
Momordioside F1 is used as an anticancer agent, capable of inhibiting the proliferation of cancer cells and inducing apoptosis. This makes it a promising candidate for the development of cancer treatments, particularly for solid malignancies.
Used in Drug Delivery Systems:
To enhance the bioavailability and therapeutic outcomes of Momordioside F1, research is ongoing to develop novel drug delivery systems. These systems aim to improve the compound's delivery to target tissues, increasing its efficacy and reducing potential side effects.

Upstream product

• 81910-38-5 momordicoside F₁ acetate 
• 81910-38-5 momordicoside G acetate 

Downstream Products

• 81910-39-6 5,19-epoxy-25-methoxy-5β-cucurbita-6,23-dien-3β-ol 
• 81910-39-6 C₃₁H₅₀O₃ 

Relevant articles and documents

Studies on the Constituents of Momordica charantia L. III. Characterization of New Cucurbitacin Glycosides of the Immature Fruits. (1). Structures of Momordicosides G, F1, F2 and I

Several non-bitter cucurbitacin glicosides were isolated together with two bitter cucurbitacin glycosides from the immature fruits of Momordica charantia L. (Cucurbitaceae), and four of the non-bitter glycosides, momordicosides G, F1, F2 and I, were caracterized from chemical and spectral evidence as folows; G, 3-O-β-D-allopyranoside of 5,19-epoxy-25-methoxy-5β-cucurbita-6,23-dien-3β-ol; F1, 3-O-β-D-glucopyranoside of 5,19-epoxy-25-methoxy-5β-cucurbita-6,23-dien-3β-ol; F2, 3-O-β-D-allopyranoside of 5,19-epoxy-5β-cucurbita-6,23-diene-3β,25-diol; I, 3-O-β-D-glucopyranoside of 5,19-epoxy-5β-cucurbita-6,23-diene-3β,25-diol.ords- Momordica charantia; Cucurbitaceae; tetracyclic triterpene glicoside; cucurbitacin; momordicosides G, F1, F2, I; allopyranoside; 5,19-epoxy-25-methoxy-5β-cucurbita-6,23-dien-3β-ol; 5,19-epoxy-5β-cucurbita-6,23-diene-3β,25-diol