81674-79-5

Basic information

• Product Name: Guaimesal
• Synonyms: Guaimesal;9-(2-methoxyphenoxy)-9-methyl-8,10-dioxabicyclo[4.4.0]deca-1,3,5-trien -7-one;2-(2-Methoxyphenoxy)-2-methyl-4H-1,3-benzodioxin-4-one;2-(2-Methoxyphenoxy)-2-methyl-1,3-benzodioxan-4-one
• CAS NO: 81674-79-5
• Molecular Formula: C₁₆H₁₄O₅
• Molecular Weight: 286.28
• Mol File: 81674-79-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 454.7 °C at 760 mmHg
• Flash Point: 203.5 °C
• Appearance: /
• Density: 1.262 g/cm³
• Vapor Pressure: 1.86E-08mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: Guaimesal(CAS DataBase Reference)
• NIST Chemistry Reference: Guaimesal(81674-79-5)
• EPA Substance Registry System: Guaimesal(81674-79-5)

Safety Data

• Hazardous Substances Data: 81674-79-5(Hazardous Substances Data)

Usage

Description

Guaimesal is a degradation product of acetylsalicylic acid, also known as aspirin, and exhibits similar effects to aspirin. It is a potential aspirin prodrug, which means it can be metabolized into aspirin in the body, providing the same therapeutic benefits as aspirin.

Uses

Used in Pharmaceutical Industry:
Guaimesal is used as an aspirin prodrug for its potential to provide the same therapeutic effects as aspirin. It is a degradation product of acetylsalicylic acid, which means it can be metabolized into aspirin in the body, offering the same benefits as aspirin, such as pain relief, fever reduction, and anti-inflammatory effects.
Additionally, Guaimesal may have potential applications in other industries, such as cosmetics or food and beverages, due to its similar properties to aspirin. However, more research and development would be needed to explore these potential applications further.

InChI:InChI=1/C16H14O5/c1-16(20-14-10-6-5-9-13(14)18-2)19-12-8-4-3-7-11(12)15(17)21-16/h3-10H,1-2H3

Upstream product

• 90-05-1 2-methoxy-phenol 
• 6689-37-8 1-methoxy-2-trimethylsilyloxybenzene 
• 5538-51-2 O-acetylsalicyloyl chloride 
• 50-78-2 aspirin 

Downstream Products

• 50-78-2 aspirin 
• 90-05-1 2-methoxy-phenol 
• 69-72-7 salicylic acid 

Relevant articles and documents

Enzymatic and nonenzymatic in vitro hydrolysis of 2-methyl-2-[2-(methoxy)phenoxy]-4H-1,3-benzodioxin-4-one and 2-methoxyphenyl O-acetylsalicylate

This paper is concerned with the synthesis and physical properties as well as the enzymatic and nonenzymatic in vitro hydrolysis of the potential aspirin prodrug MR 693 (5) and the salicylic acid prodrug guacetisalum (6). The half-lives of both prodrugs and the amount of aspirin regenerated in each hydrolytic run for 5 have been estimated over a wide range of pH values.