81727-43-7

Basic information

• Product Name: diethyl N-(o-fluorophenyl-DL-alanyl)-1-aminoethylphosphonate
• CAS NO: 81727-43-7
• Molecular Weight: 346.339
• Mol File: 81727-43-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl N-(o-fluorophenyl-DL-alanyl)-1-aminoethylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl N-(o-fluorophenyl-DL-alanyl)-1-aminoethylphosphonate(81727-43-7)
• EPA Substance Registry System: diethyl N-(o-fluorophenyl-DL-alanyl)-1-aminoethylphosphonate(81727-43-7)

Safety Data

• Hazardous Substances Data: 81727-43-7(Hazardous Substances Data)

Upstream product

• 54788-35-1 diethyl 1-aminoethylphosphonate 
• 401-28-5 Z-Phe(2F)-OH 

Relevant articles and documents

STUDIES ON THE SYNTHESIS OF CHEMOTHERAPEUTICS. PART XI. SYNTHESIS AND ANTIBACTERIAL ACTIVITIES OF PHOSPHONOPEPTIDES

A variety of phosphonopeptides, shown in 2 as a general formula, containg natural and/or unnatural amino acids were synthesized, and their in vitro antibacterial activities were examined.N-Protected amino acids were condensed with 1-amino-ethylphosphonic acid or its ester followed by deprotection and hydrolysis to give the requisite phosphonopeptides.Several compounds showed higher levels of activity against certain members of Gram-negative bacteria than those of Alafosfalin (1) as the standard phosphonopeptide.A brief discussion on structure-activity relationships is also described.