82810-44-4

Basic information

• Product Name: gonyautoxin VI
• Synonyms: gonyautoxin VI;GONYAUTOXINS6;(3aS,10aS)-2,6-Diimino-4α-[[(N-sulfocarbamoyl)oxy]methyl]-2,3,3aα,4,5,6,8,9-octahydro-1H,10H-pyrrolo[1,2-c]purine-5,10,10-triol;[[[[(3aS,10aS)-2-Amino-3aα,4,5,6,9,10-hexahydro-5,10,10-trihydroxy-6-imino-1H,8H-pyrrolo[1,2-c]purin-4α-yl]methyl]oxy]carbonyl]amidosulfuric acid;Gonyautoxin 6;GTX6;Toxin B2
• CAS NO: 82810-44-4
• Molecular Formula: C10H17N7O8S
• Molecular Weight: 395.351
• Mol File: 82810-44-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 2.51g/cm³
• Refractive Index: 1.993
• PKA: -0.42±0.38(Predicted)
• CAS DataBase Reference: gonyautoxin VI(CAS DataBase Reference)
• NIST Chemistry Reference: gonyautoxin VI(82810-44-4)
• EPA Substance Registry System: gonyautoxin VI(82810-44-4)

Safety Data

• Hazardous Substances Data: 82810-44-4(Hazardous Substances Data)

Usage

Description

Gonyautoxin VI, also known as GTX6, is a potent neurotoxin found in marine organisms, particularly shellfish, and is one of the toxins responsible for incidents of paralytic shellfish poisoning (PSP). It is a heat-stable, water-soluble compound that can cause severe neurological symptoms and even death if ingested in high concentrations. GTX6 is regulated by the European Union as a marine toxin to ensure the safety of seafood products.

Uses

Used in Research Applications:
Gonyautoxin VI is used as a research tool for studying the mechanisms of action of marine toxins and their effects on the nervous system. It helps researchers understand the molecular interactions between toxins and their target receptors, as well as the development of potential antidotes or treatments for PSP.
Used in Food Safety and Quality Control:
Gonyautoxin VI is used as a biomarker for monitoring and controlling the presence of marine toxins in shellfish and other seafood products. Regular testing for GTX6 and other toxins ensures the safety and quality of seafood, protecting consumers from the risks associated with PSP.
Used in Environmental Monitoring:
Gonyautoxin VI can be used as an indicator of harmful algal blooms (HABs) in marine ecosystems. The presence of GTX6 and other toxins in shellfish can signal the occurrence of HABs, which can have significant ecological and economic impacts. Monitoring GTX6 levels can help in the early detection and management of HABs, reducing their negative effects on marine life and human health.

InChI:InChI=1/C10H17N7O8S/c11-5-2-8-6(14-5)4(1-10(20,21)15-26(23,24)25)16(22)7(12)17(8)13-3-9(8,18)19/h3-4,6,12,15,18-22H,1-2H2,(H2,11,14)(H,23,24,25)/b12-7+/t4-,6+,8?/m1/s1

Upstream product

• 1189-71-5 isocyanate de chlorosulfonyle 

Relevant articles and documents

Dinoflagellate neurotoxins related to saxitoxin: structure and latent activity of toxins B1 and B2

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