82948-87-6

Basic information

• Product Name: (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)- EICOS
• Synonyms: (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)- EICOS;(5S,6S)-dihydroxy-(7E,9E,11Z,14Z)-*eicosatetraeno;(5S,6S)-DIHYDROXY-(7E,9E,11Z,14Z)-*EICOS ATETRAENOIC;5(S),6(S)-DiHETE Lipid Maps MS Standard;5(S),6(S)-DiHETE MaxSpecStandard
• CAS NO: 82948-87-6
• Molecular Formula: C20H32O4
• Molecular Weight: 336.46568
• Mol File: 82948-87-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 537.6°C at 760 mmHg
• Flash Point: 293°C
• Appearance: /
• Density: 1.04g/cm³
• Vapor Pressure: 8.43E-14mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: −20°C
• CAS DataBase Reference: (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)- EICOS(CAS DataBase Reference)
• NIST Chemistry Reference: (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)- EICOS(82948-87-6)
• EPA Substance Registry System: (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)- EICOS(82948-87-6)

Safety Data

• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26-36
• RIDADR: UN 1170 3/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 82948-87-6(Hazardous Substances Data)

Usage

Description

(5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)EICOS is a leukotriene compound characterized by the presence of double bonds at the 7-, 9-, 11-, and 14-positions, along with 5(S)and 6(S)-hydroxy substituents. This unique structure endows it with specific biological properties and potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
(5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)EICOS is used as a pharmaceutical agent for its potential role in modulating inflammatory responses. (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)EICOS's unique structure allows it to interact with biological targets, such as enzymes and receptors, involved in inflammatory pathways. This interaction can help in the development of drugs targeting various inflammatory conditions.
Used in Research Applications:
In the field of scientific research, (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)EICOS serves as a valuable tool for studying the mechanisms of leukotrienes and their role in various physiological and pathological processes. Its unique structure makes it an ideal candidate for investigating the effects of specific modifications on biological activity and selectivity.
Used in Drug Development:
(5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)EICOS can be employed in drug development as a lead compound or a template for designing new therapeutic agents. Its unique structural features can be exploited to create novel molecules with improved pharmacological properties, such as enhanced potency, selectivity, and reduced side effects.
Used in Analytical Chemistry:
In analytical chemistry, (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)EICOS can be utilized as a reference compound for the development and validation of analytical methods for the detection and quantification of leukotrienes and related compounds. Its unique structure and properties make it a suitable candidate for method development and optimization.
Overall, (5S 6S)-DIHYDROXY-(7E 9E 11Z 14Z)EICOS is a versatile compound with potential applications in various industries, including pharmaceuticals, research, drug development, and analytical chemistry. Its unique structure and properties make it a promising candidate for further exploration and utilization in these fields.

InChI:InChI=1/C20H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18(21)19(22)16-14-17-20(23)24/h6-7,9-13,15,18-19,21-22H,2-5,8,14,16-17H2,1H3,(H,23,24)/b7-6-,10-9-,12-11+,15-13+/t18-,19-/m0/s1

Upstream product

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• 127705-13-9 1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-4-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-butan-1-ol 
• 127705-17-3 4-((4S,5S)-5-Hydroxymethyl-2-oxo-[1,3]dioxolan-4-yl)-butyric acid methyl ester 
• 148553-24-6 (5S)-<5-oxo-(1E,3E)-penta-1,3-dien-1-yl>-2-oxo-1,3-dioxolane-4-butanoate de methyle 
• 127705-14-0 5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-5-hydroxy-pentanoic acid 3-hydroxy-2-hydroxymethyl-2-methyl-propyl ester 
• 127721-09-9 (S)-5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-5-phenoxycarbonyloxy-pentanoic acid methyl ester 

Relevant articles and documents

Stereokontrollierte Totalsynthese von (5S,6R)-, (5S,6S)-, (5R,6R)- und (5R,6S)-(7E,9E,11Z,14Z)-5,6-Dihydroxy-7,9,11,14-icosatetraensaeure-(5,6-DiHETE)methylester

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