82950-64-9

Basic information

• Product Name: (+/-)-1,2-DIDECANOYLGLYCEROL
• Synonyms: DIDECANOIN;DICAPRIN;10:0 DG;1,2-DICAPRIN;1,2-DICAPRYL-SN-GLYCEROL;(+/-)-1,2-DIDECANOYLGLYCEROL;1,2-DIDECANOYL-RAC-GLYCEROL;1,2-didecanoyl-rac-glycerol (C10:0)
• CAS NO: 82950-64-9
• Molecular Formula: C23H44O5
• Molecular Weight: 400.59
• Mol File: 82950-64-9.mol
• Article Data: 28

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: (+/-)-1,2-DIDECANOYLGLYCEROL(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-1,2-DIDECANOYLGLYCEROL(82950-64-9)
• EPA Substance Registry System: (+/-)-1,2-DIDECANOYLGLYCEROL(82950-64-9)

Safety Data

• Hazardous Substances Data: 82950-64-9(Hazardous Substances Data)

Usage

Description

(+/-)-1,2-DIDECANOYLGLYCEROL is a chemical compound that belongs to the class of glycerides, which are esters of glycerol and fatty acids. It is an important component of various natural oils and fats and is used in the production of pharmaceuticals, cosmetics, and food products. This chemical is a glyceride consisting of two decanoic acid molecules bound to a glycerol backbone.

Uses

Used in Cosmetics Industry:
(+/-)-1,2-DIDECANOYLGLYCEROL is used as an emollient and stabilizer for cosmetic products, providing a smooth and moisturizing effect on the skin.
Used in Pharmaceutical Industry:
(+/-)-1,2-DIDECANOYLGLYCEROL is used in drug delivery systems due to its ability to enhance the solubility and stability of certain drugs, potentially improving their efficacy and safety.
Used in Food Industry:
(+/-)-1,2-DIDECANOYLGLYCEROL is used in the production of food products, contributing to their texture and stability.
Additionally, (+/-)-1,2-DIDECANOYLGLYCEROL has been studied for its potential role in modulating biological processes, such as lipid metabolism and immune function, which could lead to further applications in various industries.

Upstream product

• 112-13-0 n-decanoyl chloride 
• 334-48-5 1-decanoic acid 
• 56-81-5 glycerol 
• 621-71-6 capric acid triglyceride 
• 124-07-2 Octanoic acid 
• 110-42-9 Methyl decanoate 
• 3376-48-5 2-decanoyloxy-propane-1,3-diol 
• 103160-49-2 1,2-O,O'-bisdecanoyl-3-O-benzyl-rac-glycerol 
• 110-38-3 decanoic acid ethyl ester 
• 3436-44-0 1,2-didecanoyl-sn-glycero-3-phosphocholine 
• 103160-49-2 1,2-di-O-decanoyl-3-O-benzyl-sn-glycerol 

Relevant articles and documents

Method for microwave synthesis of glyceryl caprylate-caprate

The invention provides a preparation method for microwave synthesis of glyceryl caprylate-caprate. Caprylate-caprate and glycerin are reacted in the presence of a compound catalyst, and a glyceryl caprylate-caprate product is prepared by microwave synthesis. According to the method, the molar ratio of caprylate and caprate in the glyceryl caprylate-caprate is regulated, catalysis of the compound catalyst is combined, and a frequency band of 300 to 3,000MHz is adopted for microwave synthesis, so that the high-quality glyceryl caprylate-caprate of which the molar ratio of the caprylate and the caprate is controllable can be efficiently and rapidly prepared. According to the method, a high esterification rate can be achieved, and meanwhile, the energy consumption and the production cost of a reaction process can be remarkably reduced.

Fosaprepitant derivative, synthesis thereof, and use thereof in long acting preparation

The invention relates to a Fosaprepitant derivative, a synthesis thereof, and a use thereof in a long acting preparation. The invention relates to a compound of formula (I), and a salt, an N-oxide, a quaternary ammonium and a stereoisomer thereof. R to R in the formula (I) are as defined in claims. The invention also relates to an intermediate for preparing the compound of formula (I), and a method for preparing the compound of formula (I). The invention further relates to a use of the compound of formula (I) as a drug especially used for preventing chemotherapy induced acute and late nausea and vomiting.

Enzymatic synthesis of 1,3-dicaproyglycerol by esterification of glycerol with capric acid in an organic solvent system

In this work, the esterification of glycerol with capric acid catalyzed by an immobilized form of a 1,3-positionally selective lipase (Rhizomucor miehei) showed to be effective for the synthesis of 1,3-dicaprin in n-heptane as the reaction medium. The effects of the reaction parameters were studied using an experimental factorial design of three factors and three levels with two central points. The selected experimental variables were amount of glycerol adsorbed on silica gel (G), biocatalyst load (E) and reaction temperature (T), and the response variables were total conversion of capric acid, acylglycerol fractions, selectivity and yield of dicaprin, and acyl migration reaction. The range of each parameter was selected as follows: G = 50-250 mg, E = 20-40 mg and T = 40-60 C. At optimum conditions 73% capric acid conversion was achieved, with 76% dicaprin selectivity, and selectivity to the specific 1,3-dicaprin of 70% of total products. An adequate selection of the reaction conditions is necessary not only to maximize the conversion of capric acid, but also to minimize the acyl migration reaction and the generation of undesired products. Evidence of kinetically controlled enzymatic acyl migration from sn-3/sn-1 to sn-2 is presented.