83291-49-0 Usage
Type of compound
Chemical compound
Derivative of
Fluorenone (a polycyclic aromatic hydrocarbon)
Functional group
Trimethylsilyloxy group
Role of trimethylsilyloxy group
Protecting group in organic synthesis
Purpose
Prevents unwanted interactions with reactive functional groups
Application
Used as a reagent in organic synthesis reactions
Specific use
Formation of carbon-carbon and carbon-heteroatom bonds
Health hazards
May pose health hazards if not used properly
Precaution
Handle with caution
Check Digit Verification of cas no
The CAS Registry Mumber 83291-49-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,2,9 and 1 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 83291-49:
(7*8)+(6*3)+(5*2)+(4*9)+(3*1)+(2*4)+(1*9)=140
140 % 10 = 0
So 83291-49-0 is a valid CAS Registry Number.
InChI:InChI=1/C19H20O2Si/c1-22(2,3)21-19-16-10-5-4-8-14(16)15-9-6-7-13(18(15)19)11-12-17(19)20/h4-10H,11-12H2,1-3H3
83291-49-0Relevant articles and documents
Fluoranthene: Synthesis and Mutagenicity of Four Diol Epoxides
Rastetter, William H.,Nachbar, Robert B.,Russo-Rodriguez, Sandra,Wattley, Ruth V.,Thilly, William G.,et al.
, p. 4873 - 4878 (2007/10/02)
The syntheses of diol epoxides 4a,b and 5a,b of the mutagenic hydrocarbon fluoranthene (1) are described.Standard methodology is applied to the synthesis of targets 4a,b but fails for the synthesis of 5a,b.The latter two diol epoxides can be assembled by a route utilizing stereoselective, directed epoxidations.Simple molecular orbital calculations have been used to predict the reactivity of the diol epoxides in their opening to triol carbocations.Diol epoxides 4a,b are predicted to be substantially more reactive than isomers 5a,b.The more reactive pair, 4a,b, mayyield carbocations capable of alkylating cellular genetic material.This prediction is borne out in terms of the relative mutagenicity of the diol epoxides in a bacterial screen.