835627-60-6

Basic information

• Product Name: Acetamide, N-[2-(acetylamino)-4-methylphenyl]-N-[2-(acetyloxy)ethyl]-
• CAS NO: 835627-60-6
• Molecular Formula: C15H20N2O4
• Molecular Weight: 292.335
• Mol File: 835627-60-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[2-(acetylamino)-4-methylphenyl]-N-[2-(acetyloxy)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2-(acetylamino)-4-methylphenyl]-N-[2-(acetyloxy)ethyl]-(835627-60-6)
• EPA Substance Registry System: Acetamide, N-[2-(acetylamino)-4-methylphenyl]-N-[2-(acetyloxy)ethyl]-(835627-60-6)

Safety Data

• Hazardous Substances Data: 835627-60-6(Hazardous Substances Data)

Upstream product

• 100418-33-5 4-[(2'-hydroxyethyl)amino]-3-nitro-1-methylbenzene 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Synthesis of imidazo[1,5,4-de]quinoxalin-9-ones, benzimidazole analogues of pyrroloiminoquinone marine natural products

The imidazoquinoxalinones 1 and 2 are benzimidazole analogues of indole-based marine natural products called makaluvamins. The stabilized cation 1 and the zwitterion 2 were prepared in ～9 steps from readily available starting materials. Compound 1 is more cytostatic and cytotoxic than 2 and also shows activity in the hollow fiber assay. Unlike the indole-based natural products, 1 and 2 are not potent topoisomerase II inhibitors. Their pattern of cytotoxic and cyostatic activity could be related to inhibition of protein tyrosine kinases.