836608-01-6Relevant articles and documents
Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux
Lorendeau, Doriane,Dury, Lauriane,Genoux-Bastide, Estelle,Lecerf-Schmidt, Florine,Sim?es-Pires, Claudia,Carrupt, Pierre-Alain,Terreux, Rapha?l,Magnard, Sandrine,Di Pietro, Attilio,Boumendjel, Ahcène,Baubichon-Cortay, Hélène
, p. 235 - 245 (2014/07/21)
The multidrug resistance protein 1 (MRP1) is involved in multidrug resistance of cancer cells by mediating drug efflux out of cells, often in co-transport with glutathione (GSH). GSH efflux mediated by MRP1 can be stimulated by verapamil. In cells overexp
Efficient synthesis of nitroflavones by cyclodehydrogenation of 2prime;-hydroxychalcones and by the Baker-Venkataraman method
Barros, Ana I. R. N. A.,Silva, Artur M. S.
, p. 1505 - 1528 (2007/10/03)
Several nitroflavone derivatives were synthesized by cyclodehydrogenation of 2′-hydroxychalcones and by the Baker-Venkataraman approach, starting from 2′-hydroxyacetophenones and benzoic acid derivatives. Nitroflavones synthesised by the first synthetic a