84-85-5

Basic information

• Product Name: 4-METHOXY-1-NAPHTHOL
• Synonyms: 1,4-DIHYDROXYNAPHTHALENE MONOMETHYL ETHER;1-HYDROXY-4-METHOXYNAPHTHALENE;4-METHOXYNAPHTHALEN-1-OL;4-METHOXY-1-NAPHTHOL;4-METHOXY-1-NAPHTHOL, 97+%;4-Methoxy-1-naphthol, 98+%;4-Methoxy-1-naphthol 98%;4-methoxy-1-naphthaleno
• CAS NO: 84-85-5
• Molecular Formula: C₁₁H₁₀O₂
• Molecular Weight: 174.2
• EINECS: 201-566-3
• Product Categories: Industrial/Fine Chemicals;Naphthalene derivatives
• Mol File: 84-85-5.mol
• Article Data: 25

Chemical Properties

• Melting Point: 126-129 °C(lit.)
• Boiling Point: 265.17°C (rough estimate)
• Flash Point: 228.6 °C
• Appearance: grey to brown-purple crystalline powder
• Density: 1.0844 (rough estimate)
• Vapor Pressure: 2.23E-05mmHg at 25°C
• Refractive Index: 1.5250 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 10.24±0.40(Predicted)
• Water Solubility: Soluble in water.
• BRN: 1818465
• CAS DataBase Reference: 4-METHOXY-1-NAPHTHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-1-NAPHTHOL(84-85-5)
• EPA Substance Registry System: 4-METHOXY-1-NAPHTHOL(84-85-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 84-85-5(Hazardous Substances Data)

Usage

Chemical Properties

GREY TO BROWN-PURPLE CRYSTALLINE POWDER

Uses

Different sources of media describe the Uses of 84-85-5 differently. You can refer to the following data:
1. 4-Methoxynaphthalen-1-ol is a novel antibacterial compound targeting the WalK/WalR two-component signal transduction system of Gram (+) bacteria. walrycin A is a novel human PXR activator, that induces human PXR transcriptional activity. 4-Methoxynaphthalen-1-ol is a WalR inhibitors, a novel antibacterial compound specifically targeting essential WalR response regulator.
2. 4-Methoxy-1-naphthol was used in the synthesis of 3-(4-hydroxy-1-naphthoxy)lactic acid (4-HO-NLA).

InChI:InChI=1/C11H10O2/c1-13-11-7-6-10(12)8-4-2-3-5-9(8)11/h2-7,12H,1H3

Upstream product

• 67-56-1 methanol 
• 571-60-8 1,4-Dihydroxynaphthalene 
• 2834-90-4 4-amino-1-naphthol 
• 130-15-4 [1,4]naphthoquinone 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 77-78-1 dimethyl sulfate 
• 99893-90-0 4-(2-Bromethoxy)-1-naphthol 
• 2216-69-5 1-Methoxynaphthalene 
• 95-56-7 2-hydroxybromobenzene 
• 59010-83-2 1-methyl-4-(2-hydroxylphenyl)thiobenzene 
• 1609120-00-4 2-(4-tolylthio)phenyl triflate 
• 25414-22-6 2-methoxyfuran 
• 1609119-99-4 2-(p-tolylsulfinyl)phenyl triflate 

Downstream Products

• 108774-65-8 acetic acid-[4-(2-hydroxy-4-methoxy-[2]naphthylazo)-anilide] 
• 59900-33-3 4-methoxy-2-[(E)-phenyldiazenyl]naphthalen-1-ol 
• 139016-14-1 (+/-)-trans-2-(3,4-dimethoxyphenyl)-2,3-dihydro-5-methoxy-3-methylnaphtho<1,2-b>furan 
• 10075-62-4 1,4-dimethoxynaphthalene 
• 123239-56-5 4-methoxy-2-benzoyl-1-naphthol 
• 139016-16-3 (+/-)-trans-2-(4-methoxyphenyl)-2,3-dihydro-5-methoxy-3-methylnaphtho<1,2-b>furan 
• 14133-78-9 1-Methoxy-4-(2,3-epoxy)propoxynaphthalene 
• 130-15-4 [1,4]naphthoquinone 
• 3408-13-7 2,2'-binaphthoquinone 
• 82663-57-8 4,4′-dimethoxy-2,2′-binaphthalenyl-1,1′-diol 
• 853362-15-9 1-methoxy-4-(3-{2-[3-(4-nitro-phenoxy)-prop-1-ynyl]-phenyl}-prop-2-ynyloxy)-naphthalene 
• 177028-18-1 2-acetyl-4-methoxy-1-naphthol-p-tosylate 

Relevant articles and documents

Synthesis of propanolamine side chain deuterated propanolol, propranolol-diol and 4-hydroxypropranolol

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Tuning the Reactivity of Peroxo Anhydrides for Aromatic C-H Bond Oxidation

Phenol moieties are key structural motifs in many areas of chemical research from polymers to pharmaceuticals. Herein, we report on the design and use of a structurally demanding cyclic peroxide (spiro[bicyclo[2.2.1]heptane-2,4′-[1,2]dioxolane]-3′,5′-dione, P4) for the direct hydroxylation of aromatic substrates. The new peroxide benefits from high thermal stability and can be synthesized from readily available starting materials. The aromatic C-H oxidation using P4 exhibits generally good yields (up to 96%) and appreciable regioselectivities.

Condensed compound and organic light emitting diode comprising the same

Disclosed are a condensed ring compound and an organic light emitting diode. The organic light emitting diode has low driving voltage, high efficiency, high brightness, and long life. The organic light emitting diode includes a first electrode; a second electrode facing the first electrode; and an organic layer interposed between the first electrode and the second electrode, and including a light emitting layer, wherein the organic layer includes one or more kind of condensed ring compound of any one claim among a first claim to 15^th claim.COPYRIGHT KIPO 2015