846038-66-2 Usage
Chemical structure
The compound has a complex structure that includes a naphthyridine ring system, a piperazine moiety, and a 1-benzopyran ring system.
DNA-PK inhibition
It is a potent inhibitor of DNA-dependent protein kinase (DNA-PK), which is involved in the non-homologous end joining (NHEJ) repair of DNA double-strand breaks.
Potential cancer treatment
Inhibiting DNA-PK can be used as a strategy to sensitize cancer cells to DNA-damaging agents such as chemotherapy and radiation therapy.
Piperazine moiety
The presence of the piperazine moiety in the compound suggests the potential for interactions with receptors or transporters.
Drug candidate potential
Due to its DNA-PK inhibition and the presence of the piperazine moiety, the compound is a candidate for further study as a potential drug candidate.
Molecular weight
The molecular weight of the compound is approximately 468.55 g/mol.
Appearance
The compound is likely to be a solid, based on its molecular weight and complexity.
Solubility
The compound's solubility is not specified in the provided material, but it may be soluble in organic solvents such as dimethyl sulfoxide (DMSO) or methanol.
Stability
The stability of the compound under various conditions (e.g., temperature, pH, light) is not specified in the provided material, but it may be sensitive to light, heat, or moisture.
Check Digit Verification of cas no
The CAS Registry Mumber 846038-66-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,6,0,3 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 846038-66:
(8*8)+(7*4)+(6*6)+(5*0)+(4*3)+(3*8)+(2*6)+(1*6)=182
182 % 10 = 2
So 846038-66-2 is a valid CAS Registry Number.