84666-28-4

Basic information

• Product Name: 4-Chloromethyl-6-methoxy-2-p-tolyl-quinoline
• Synonyms: 4-Chloromethyl-6-methoxy-2-p-tolyl-quinoline
• CAS NO: 84666-28-4
• Molecular Weight: 297.784
• Mol File: 84666-28-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Chloromethyl-6-methoxy-2-p-tolyl-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloromethyl-6-methoxy-2-p-tolyl-quinoline(84666-28-4)
• EPA Substance Registry System: 4-Chloromethyl-6-methoxy-2-p-tolyl-quinoline(84666-28-4)

Safety Data

• Hazardous Substances Data: 84666-28-4(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 104-94-9 4-methoxy-aniline 
• 18193-09-4 2-(p-tolyl)-6-methoxy-4-quinolinecarboxylic acid 

Downstream Products

• 462628-10-0 6-methoxy-4-(3-phenyl-propoxymethyl)-2-p-tolyl-quinoline 
• 462628-09-7 4-(4-chloro-phenoxymethyl)-6-methoxy-2-p-tolyl-quinoline 
• 117839-39-1 6-methoxy-4-methyl-2-(p-tolyl)quinoline 
• 112500-20-6 6-Methoxy-2-p-tolyl-quinoline-4-carbaldehyde 
• 84666-27-3 2-(p-tolyl)-6-methoxy-4-quinolinemethanol 
• 462628-08-6 6-methoxy-4-phenoxymethyl-2-p-tolyl-quinoline 
• 462628-12-2 4-[2-((1R,5S)-6,6-Dimethyl-bicyclo[3.1.1]hept-2-en-2-yl)-ethoxymethyl]-6-methoxy-2-p-tolyl-quinoline 
• 462628-11-1 6-methoxy-4-octyloxymethyl-2-p-tolyl-quinoline 
• 84666-29-5 2-(6-Methoxy-2-p-tolyl-quinolin-4-ylmethyl)-isothiourea 

Relevant articles and documents

Synthesis and Photocleavage of Quinoline Methyl Ethers: A Mild and Efficient Method for the Selective Protection and Deprotection of the Alcohol Functionality

The synthesis and photocleavage of quinolinyl methyl ether-protected alcohols is reported in this study. A variety of quinoline methyl chlorides were synthesized, and protection of the various alcohols was performed via a substitution reaction in the presence of a strong base. Photocleavage of the quinolinyl methyl ether moiety proceeded under visible light with the formation of the charged quinolinyl radical intermediate through a single-electron transfer in the presence of a photosensitizer dye leading to the deprotected alcohol in excellent yields. The utility of triethylamine as a sacrificial reductant and d-sorbitol as a radical scavenger were also investigated in this study.

A NEW PHOTOCHEMICALLY REMOVABLE PROTECTING GROUP FOR AMINES

A new arylmethylsulfonyl chloride reacts with secondary or primary amines to give sulfonamides which can be photochemically cleaved, making it suitable for use as a photoremovable protecting group.