849110-27-6

Basic information

• Product Name: 1H-Imidazole-4-carbonitrile, 5-amino-1-(4-hydroxyphenyl)-
• CAS NO: 849110-27-6
• Molecular Formula: C10H8N4O
• Molecular Weight: 200.2
• Mol File: 849110-27-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole-4-carbonitrile, 5-amino-1-(4-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-4-carbonitrile, 5-amino-1-(4-hydroxyphenyl)-(849110-27-6)
• EPA Substance Registry System: 1H-Imidazole-4-carbonitrile, 5-amino-1-(4-hydroxyphenyl)-(849110-27-6)

Safety Data

• Hazardous Substances Data: 849110-27-6(Hazardous Substances Data)

Upstream product

• 1233851-80-3 C₁₁H₉N₅O 

Downstream Products

• 1610624-78-6 C₁₇H₁₂N₄O₃ 
• 1610624-79-7 C₁₇H₁₂N₄O₄ 
• 1610624-80-0 C₁₇H₁₂N₄O₄ 
• 1610624-81-1 C₁₇H₁₂N₄O₄ 

Relevant articles and documents

Adenine Derivatives: Promising Candidates for Breast Cancer Treatment

The cascade reaction of N-aryl-5-{[(dimethylamino)methylene]amino}-4-cyanoimidazoles with primary aromatic amines, under reflux in acetic acid, proved to be a general and efficient method for the regioselective synthesis of 6-arylaminopurines. A selection of these compounds was tested in breast cancer cell models MCF-7 and Hs578t and five compounds proved to be highly active and non-toxic to the non-neoplastic cell line MCF-10A. Furthermore, the compounds demonstrated apoptosis-inducing capacity in the cancer cells.