85-17-6 Usage
Description
Streptidine is an amino cyclitol that is scyllo-inositol in which the hydroxy groups at positions 1 and 3 are replaced by guanidino groups.
Uses
Used in Pharmaceutical Industry:
Streptidine is used as a key component in the development of antibiotics, particularly in the synthesis of streptomycin, a broad-spectrum antibiotic effective against both gram-positive and gram-negative bacteria. Its unique structure allows it to bind to bacterial ribosomes, inhibiting protein synthesis and ultimately leading to bacterial cell death.
Used in Research Applications:
Streptidine is utilized as a research tool in the study of bacterial resistance mechanisms, as well as in the development of new antibiotics and drug delivery systems. Its ability to target specific bacterial components makes it a valuable asset in understanding and combating antibiotic resistance.
Used in Diagnostic Applications:
Streptidine can be employed as a diagnostic agent in the identification and differentiation of bacterial species, particularly those susceptible to streptomycin. Its unique chemical properties allow for the development of tests and assays that can accurately detect the presence of specific bacteria in clinical samples.
Check Digit Verification of cas no
The CAS Registry Mumber 85-17-6 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 5 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 85-17:
(4*8)+(3*5)+(2*1)+(1*7)=56
56 % 10 = 6
So 85-17-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H18N6O4/c9-7(10)13-1-3(15)2(14-8(11)12)5(17)6(18)4(1)16/h1-6,15-18H,(H4,9,10,13)(H4,11,12,14)/t1-,2+,3?,4+,5-,6?
85-17-6Relevant articles and documents
Rescue of the streptomycin antibiotic activity by using streptidine as a "decoy acceptor" for the aminoglycoside-inactivating enzyme adenyl transferase
Latorre, Montserrat,Penalver, Pablo,Revuelta, Julia,Asensio, Juan Luis,Garcia-Junceda, Eduardo,Bastida, Agatha
, p. 2829 - 2831 (2007)
The use of streptidine as a "decoy acceptor" allows the antibiotic activity of streptomycin to recover against the Escherichia coli strain overexpressing the aminoglycoside-modifying enzyme 6-O-adenyl transferase. The Royal Society of Chemistry.
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Peck et al.
, p. 29 (1946)
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