85068-28-6 Usage
Description
2,6-Difluorophenylacetic acid is an organic compound characterized by the presence of two fluorine atoms at the 2nd and 6th positions on a phenylacetic acid structure. This unique molecular arrangement endows it with specific chemical properties that make it a versatile building block in various synthetic applications.
Uses
Used in Pharmaceutical and Chemical Synthesis:
2,6-Difluorophenylacetic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds and organic molecules. Its distinctive structure allows for the development of new drugs with potential therapeutic applications.
Used in the Synthesis of α-Azidoacetophenones:
2,6-Difluorophenylacetic acid is utilized as a starting material for the production of α-azidoacetophenones, which are important in the synthesis of biologically active compounds and have potential applications in medicinal chemistry.
Used in the Synthesis of N-(2,6-Difluorobenzyl)-N′-(1H-5-indazolyl)urea:
2,6-Difluorophenylacetic acid is also employed in the creation of N-(2,6-difluorobenzyl)-N′-(1H-5-indazolyl)urea, which may have applications in research and development for new pharmaceutical agents, given the presence of the indazole moiety that is often found in biologically active molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 85068-28-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,0,6 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 85068-28:
(7*8)+(6*5)+(5*0)+(4*6)+(3*8)+(2*2)+(1*8)=146
146 % 10 = 6
So 85068-28-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F2O2/c9-6-2-1-3-7(10)5(6)4-8(11)12/h1-3H,4H2,(H,11,12)
85068-28-6Relevant articles and documents
Synthesis of dihalophenylacetic acids using aromatic nucleophilic substitution strategy
Kowalczyk, Bruce A.
, p. 1411 - 1414 (2007/10/03)
A simple synthetic strategy to dihalophenylacetic acids and specifically 3,5-difluorophenylacetic acid an important pharmaceutical intermediate was developed. The aromatic nucleophilic substitution of dihalofluorobenzenes using the anion of ethyl cyanoacetate yielded ethyl dihalophenylcyanoacetates. The basic decarboxylation of the ethyl dihalophenylcyanoacetates produced targeted dihalophenylacetic acids.
