850868-88-1Relevant articles and documents
The synthetic preparation of naturally-occurring aromatase inhibitors, morachalcone A, isogemichalcone B, and isogemichalcone C
Brandt, Drew R.,Pannone, Kristina M.,Romano, Joseph J.,Casillas, Eduard G.
, p. 9994 - 10002 (2013/11/06)
A convergent synthesis applicable to the preparation of oxidized prenylchalcones is reported that relies on key Claisen-Schmidt, Mitsunobu, and vinyl/benzyl Stille coupling operations. The synthetic strategy was applied towards the preparation of the natu
A short synthesis of morachalcone A
Romano, Joseph J.,Casillas, Eduard
, p. 2323 - 2326 (2007/10/03)
Advanced C-prenylated intermediates for three aromatase inhibitors, including morachalcone A, can be synthesized through a Claisen-Schmidt condensation followed by Florisil-catalyzed [1,3]-sigmatropic rearrangement of a prenyl phenyl ether.