850895-65-7Relevant articles and documents
COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY
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Page/Page column 188-189, (2020/12/30)
This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.
Phenoxypropanol connected with phenylpiperazine and phenoxyalkylamine terminal in its side chain
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, (2008/06/13)
The invention disclosed some 1,4-dihydropiridine derivative chemically have pharmacologically with adrenoceptor blocking and calcium channel blocker is now emerging. The compound of 1,4-dihydropiridine derivative wherein has the formula I, wherein R selected from four group as follow whetherin R present R1 selected from halogen(X), hydrogen(H), saturated C1-C6 alkyl chain, saturated C1-C6 alkyoxyl chain, R2 selected from R3 selected from halogen(X), hydrogen(H), saturated C1-C6 alkyl chain, saturated C1-C6 alkyoxyl chain, and O—(C1-C3)—CF3.
