85170-78-1

Basic information

• Product Name: (S)-((1R,2R,4R)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid
• Synonyms: (S)-((1R,2R,4R)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid
• CAS NO: 85170-78-1
• Molecular Weight: 288.387
• Mol File: 85170-78-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-((1R,2R,4R)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-((1R,2R,4R)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid(85170-78-1)
• EPA Substance Registry System: (S)-((1R,2R,4R)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid(85170-78-1)

Safety Data

• Hazardous Substances Data: 85170-78-1(Hazardous Substances Data)

Upstream product

• 103-82-2 phenylacetic acid 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 

Downstream Products

• 137678-81-0 (-)-(1S,2R,5S,7R)-2-phenyl-5,6,6-trimethyl-4-oxatricyclo<5.2.1.0^1,5>decan-3-one 
• 84946-08-7 (1R,4R)-(-)-(E)-2-benzylidene-1,7,7-trimethylbicyclo<2.2.1>heptane 
• 107729-84-0 (1R,2R,4R,3'S)-(-)-3'-phenyl-1,7,7-trimethyl-spiro (bicyclo-<2.2.1>heptane-2,2'-oxetan)-4'-one 
• 137678-81-0 (+)-(1S,2S,5S,7R)-2-phenyl-5,6,6-trimethyl-4-oxatricyclo<5.2.1.0^1,5>decan-3-one 
• 137678-81-0 (+)-(1S,2S,5R,7R)-2-phenyl-5,6,6-trimethyl-4-oxatricyclo<5.2.1.0^1,5>decan-3-one 
• 94013-38-4 ((1S,2S,4S)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid 2-dimethylamino-ethyl ester; hydrochloride 
• 94013-38-4 ((1R,2S,4R)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid 2-dimethylamino-ethyl ester; hydrochloride 
• 94013-38-4 ((1R,2R,4R)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid 2-dimethylamino-ethyl ester; hydrochloride 
• 94013-38-4 ((1R,2S,4R)-2-Hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-phenyl-acetic acid 2-dimethylamino-ethyl ester; hydrochloride 

Relevant articles and documents

Stereochemistry of the addition of Ivanov magnesium reagents to camphor and norchamphor

The arylacetic acid magnesium reagents (Ivanov reagents) react with (+)-camphor or (+/-)-norcamphor to give diastereoisomeric β-hydroxy acids.Under kinetic control the sole products are the endo isomers for camphor and exo isomers for norcamphor.Conversely, under equilibrium conditions exo addition is preferred for camphor and endo for norcamphor, i.e. the nucleophile enters from the more hintered side.On treatment with thionyl chloride the hydroxy acids easily afford spiro-β-lactones.The latter stereospecifically afford olefins which permit a chemical correlation.