85236-51-7

Basic information

• Product Name: Phenol, 4-amino-2,6-bis(1-pyrrolidinylmethyl)-
• CAS NO: 85236-51-7
• Molecular Formula: C16H25N3O
• Molecular Weight: 275.394
• Mol File: 85236-51-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenol, 4-amino-2,6-bis(1-pyrrolidinylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-amino-2,6-bis(1-pyrrolidinylmethyl)-(85236-51-7)
• EPA Substance Registry System: Phenol, 4-amino-2,6-bis(1-pyrrolidinylmethyl)-(85236-51-7)

Safety Data

• Hazardous Substances Data: 85236-51-7(Hazardous Substances Data)

Upstream product

• 100-02-7 4-nitro-phenol 
• 103-90-2 4-acetaminophenol 
• 121836-29-1 4-nitro-2,6-bis(pyrrolidin-1'-ylmethyl)phenol 
• 81079-95-0 3,5-bis<(N-pyrrolidinyl)methyl>-4-hydroxyacetanilide 

Downstream Products

• 95257-88-8 4-<3,5-bis<(N-pyrrolidinyl)methyl>-4-hydroxyanilino>-7-(trifluoromethyl)quinoline 
• 130291-24-6 2,6-bis(pyrrolidin-1'-ylmethyl)-4-(7''-trifluoromethyl-1'',5''-naphthyridin-4''-ylamino)phenol 
• 343935-64-8 4-Chloro-N-[3,5-bis(1-pyrrolidinomethyl)-4-hydroxyphenyl]benzenesulfonamide 
• 129210-19-1 2,6-bis(pyrrolidin-1'-ylmethyl)-4-(7''-trifluoromethylquinazolin-4''-ylamino)phenol 
• 5201-88-7 4-<3,5-bis<(N-pyrrolidinyl)methyl>-4-hydroxyanilino>-7-chloroquinoline 

Relevant articles and documents

Microwave-induced Mannich reaction - Synthesis of some Mannich derivatives of p-aminophenol

Mono and bis substituted dialkylamino alkyl-p-aminophenol 3 are prepared by treating paracetamol 1 with formaldehyde and appropriate secondary amines followed by deacetylation using 6 M HCI in unmodified domestic microwave oven in unsealed borosil vessels

Potential Antimalarials. VII. Di-Mannich Bases of 4-aminophenol via 4-Nitrophenols

A series of di-Mannich bases have been prepared from 4-nitrophenol and paraformaldehyde with dimethylamine, diethylamine, dipropylamine, N-(2'-hydroxyethyl)methylamine, piperidine, 3- and 4-methylpiperidine, 3,5-dimethylpiperidine or pyrrolidine.These nit

Synthesis and Antiarrhythmic and Parasympatholytic Properties of Substituted Phenols. 1. Heteroarylamine Derivatives

Twenty-four structural derivatives of the antiarrhythmic drug changrolin were synthesized and tested for antiarrhythmic and parasympatholytic activities.It was found that while the bis(pyrrolidinylmethyl)phenol pattern of changrolin appeared to be optimal