85438-53-5

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2,2'-(sulfonyldi-4,1-phenylene)bis-
• Synonyms: Phthalimide, N,N'-(sulfonyldi-p-phenylene)di- (7CI); NSC 243497
• CAS NO: 85438-53-5
• Molecular Formula: C28H16 N2 O6 S
• Molecular Weight: 508.511
• Mol File: 85438-53-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 780.9°Cat760mmHg
• Flash Point: 426.1°C
• Density: 1.529g/cm³
• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2,2'-(sulfonyldi-4,1-phenylene)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2,2'-(sulfonyldi-4,1-phenylene)bis-(85438-53-5)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2,2'-(sulfonyldi-4,1-phenylene)bis-(85438-53-5)

Safety Data

• Hazardous Substances Data: 85438-53-5(Hazardous Substances Data)

Usage

Chemical Class

Isoindole derivatives

Physical State

White solid substance

Common Uses

Building block in the synthesis of pharmaceuticals and organic compounds, dye intermediate, pigment in manufacturing, production of agrochemicals and specialty chemicals

Known For

Versatile chemical properties and unique chemical structure.

Upstream product

• 85-44-9 phthalic anhydride 
• 149131-31-7 2-{4-[(4-aminophenyl)sulfonyl]phenyl}-1H-isoindole-1,3(2H)-dione 

Relevant articles and documents

Synthesis and in vitro anti Mycobacterium tuberculosis activity of a series of phthalimide derivatives

New phthalimide derivatives were easily prepared through condensation of phthalic anhydride and selected amines with variable yields (70-90%). All compounds (3a-l) were evaluated against Mycobacterium tuberculosis H37Rv using Alamar Blue susceptibility. The compounds 3c, 3i, and 3l have the minimum inhibitory concentrations (MICs) of 3.9, 7.8, and 5.0 μg/mL, respectively, and could be considered new lead compounds in the treatment of tuberculosis and multi-drug resistant tuberculosis. Crown Copyright