854601-70-0 Usage
Description
Naloxegol is an organic heteropentacyclic compound derived from naloxone, with a PEG (polyethylene glycol) moiety replacing the keto group. It is a peripherally-selective opioid antagonist, designed to treat opioid-induced constipation.
Uses
Used in Pharmaceutical Industry:
Naloxegol is used as a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation. It works by blocking the peripheral effects of opioids on the gastrointestinal tract, thereby reducing constipation without affecting the central nervous system's pain relief properties. This selective action makes it a valuable therapeutic option for patients requiring long-term opioid therapy for chronic pain management.
Check Digit Verification of cas no
The CAS Registry Mumber 854601-70-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,4,6,0 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 854601-70:
(8*8)+(7*5)+(6*4)+(5*6)+(4*0)+(3*1)+(2*7)+(1*0)=170
170 % 10 = 0
So 854601-70-0 is a valid CAS Registry Number.
854601-70-0Relevant articles and documents
Naloxegol Oxalate and Solid Dispersion thereof
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, (2021/11/05)
The present invention relates to solid dispersion of Naloxegol oxalate. Further, the present invention relates to an improved process for Naloxegol oxalate and intermediates thereof.
NALOXEGOL OXALATE AND SOLID DISPERSION THEREOF
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, (2018/06/12)
The present invention relates to solid dispersion of Naloxegol oxalate. Further, the present invention relates to an improved process for Naloxegol oxalate and intermediates thereof.
