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855290-54-9

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855290-54-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 855290-54-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,5,2,9 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 855290-54:
(8*8)+(7*5)+(6*5)+(5*2)+(4*9)+(3*0)+(2*5)+(1*4)=189
189 % 10 = 9
So 855290-54-9 is a valid CAS Registry Number.

855290-54-9Relevant articles and documents

Selective Inhibitors of Monoamine Oxidase. 2. Arylamide SAR

Harfenist, Morton,Joyner, Charles T.,Mize, Patrick D.,White, Helen L.

, p. 2085 - 2089 (2007/10/02)

Monoamine oxidase (MAO) exists in two forms distinguishable by substrate specificity.Inhibition of MAO A is believed to be responsible for the antidepressant activity of MAO inhibitors.A group of N-arylacetamides are highly specific inhibitors of MAO A, some with IC50 values in the 10-100 nM range.The requirements for high activity and specificity include a nearly linear tricyclic aromatic portion but a larger and a smaller central ring component.The amide group, which is best acetamido, is optimally placed para to the smaller central group.The size and shape of the aromatic moiety appear to be the major influence on activity and specificity for MAO A.

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