85650-20-0

Basic information

• Product Name: 2-chloroethyl (4-nitrophenyl)methanesulfonate
• CAS NO: 85650-20-0
• Molecular Formula: C₉H₁₀ClNO₅S
• Molecular Weight: 279.6974
• Mol File: 85650-20-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 495.6°C at 760 mmHg
• Flash Point: 253.5°C
• Density: 1.476g/cm³
• Vapor Pressure: 1.78E-09mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 2-chloroethyl (4-nitrophenyl)methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloroethyl (4-nitrophenyl)methanesulfonate(85650-20-0)
• EPA Substance Registry System: 2-chloroethyl (4-nitrophenyl)methanesulfonate(85650-20-0)

Safety Data

• Hazardous Substances Data: 85650-20-0(Hazardous Substances Data)

Upstream product

• 107-07-3 2-chloro-ethanol 
• 4025-75-6 (4-nitrophenyl)methanesulfonyl chloride 

Relevant articles and documents

2-Haloethylating Agents for Cancer Chemoterapy. 2-Haloethyl Sulfonates

Because certain (2-chloroethyl)triazenes and (2-haloethyl)nitrosoureas have high antineoplastic activity, 2-chloroethyl and 2-fluoroethyl sulfonates were prepared to try to develop additional types of 2-haloethylating agents.In this initial study, it was demonstrated that antineoplastic activity much superior to that of the prototype, 2-chloroethyl methanesulfonate, could be found among 2-chloroethyl sulfonates.Among a variety of 2-chloroethyl alkane- and arenesulfonates, several substituted methanesulfonates displayed significant activity agains P388 leukemia in mice; the chloromethanesulfonat e showed high activity (T/C = 218percent).None of the arenesulfonates were active in this test.