86239-04-5

Basic information

• Product Name: Benzoic acid, 4-(fluoromethyl)-, ethyl ester
• CAS NO: 86239-04-5
• Molecular Formula: C10H11FO2
• Molecular Weight: 182.195
• Mol File: 86239-04-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(fluoromethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(fluoromethyl)-, ethyl ester(86239-04-5)
• EPA Substance Registry System: Benzoic acid, 4-(fluoromethyl)-, ethyl ester(86239-04-5)

Safety Data

• Hazardous Substances Data: 86239-04-5(Hazardous Substances Data)

Upstream product

• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 583-02-8 ethyl 4-(trifluoromethyl)benzoate 
• 373-52-4 bromofluoromethane 
• 4334-88-7 p-ethoxycarbonylphenylboronic acid 
• 26496-94-6 Ethyl 4-(bromomethyl)benzoate 

Downstream Products

• 86238-99-5 diethyl 4-(carbethoxy-α-fluorobenzyl)phosphonate 
• 86238-98-4 ethyl 4-(bromofluoromethyl)benzoate 

Relevant articles and documents

Electrochemical-Promoted Nickel-Catalyzed Oxidative Fluoroalkylation of Aryl Iodides

This work describes a general strategy for metal-catalyzed cross-coupling of fluoroalkyl radicals with aryl halides under electrochemical conditions. The contradiction between anodic oxidation of fluoroalkyl sulfinates and cathodic reduction of low-valent nickel catalysts can be well addressed by paired electrolysis, allowing for direct introduction of fluorinated functionalities into aromatic systems.

Monofluoroalkyl-containing compound and its preparation method and use

The invention discloses a monofluoroalkyl-containing compound and its preparation method. The preparation method comprises that in a solvent, in the presence of an alkali, an additive, a ligand and a catalyst, a compound A and a compound B undergo a suzuk

Aromatic Retinoic Acid Analogues. 2. Synthesis and Pharmacological Activity

Aromatic analogues of (E)-1-(4-carboxyphenyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene (1b) and its ethyl ester (1a) were synthesized as potential chemopreventive agents for the treatment of epithelial cancer and such skin diseases as psoriasis and cystic acne.The phenyl ring of 1 was replaced by 2-fluorophenyl, 2-methoxyphenyl, thienyl, furanyl, and pyridyl groups.The 1-fluorobutadiene analogue of 1 was also synthesized.With exception for the furanyl analogue, these compounds demonstrated good activity in reversing keratinization in hamster tracheal organ culture and in inhibiting the induction of ornithine decarboxylase in mouse epidermis by a tumor promoter.