863870-75-1

Basic information

• Product Name: 2-BROMO-3-FLUOROPHENYL N,N-DIETHYLCARBAMATE
• Synonyms: 2-BROMO-3-FLUOROPHENYL N,N-DIETHYLCARBAMATE
• CAS NO: 863870-75-1
• Molecular Formula: C₁₁H₁₃BrFNO₂
• Molecular Weight: 290.13
• Product Categories: pharmacetical
• Mol File: 863870-75-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 320.4°C at 760 mmHg
• Flash Point: 147.6°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 0.000318mmHg at 25°C
• Refractive Index: 1.528
• CAS DataBase Reference: 2-BROMO-3-FLUOROPHENYL N,N-DIETHYLCARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-3-FLUOROPHENYL N,N-DIETHYLCARBAMATE(863870-75-1)
• EPA Substance Registry System: 2-BROMO-3-FLUOROPHENYL N,N-DIETHYLCARBAMATE(863870-75-1)

Safety Data

• Hazardous Substances Data: 863870-75-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H13BrFNO2/c1-3-14(4-2)11(15)16-9-7-5-6-8(13)10(9)12/h5-7H,3-4H2,1-2H3

Upstream product

• 205187-05-9 3-fluorophenyl N,N-diethyl-O-carbamate 
• 88-10-8 N,N-diethylcarbamyl chloride 
• 372-20-3 3-fluorophenol 

Downstream Products

• 111721-75-6 2-bromo-3-fluoroaniline 
• 1287791-74-5 N-(2-bromo-3-fluorophenyl)-2-hydroxy-2-methylpropanamide 
• 1287791-64-3 2-(2-bromo-3-fluorophenoxy)-2-methylpropanamide 
• 443-81-2 2-bromo-3-fluorophenol 

Relevant articles and documents

Approaches to the synthesis of 2,3-dihaloanilines. Useful precursors of 4-functionalized-1 H-indoles

2,3-Dihaloanilines have been proved as useful starting materials for synthesizing 4-halo-1H-indoles. Subsequent or in situ functionalization of the prepared haloindoles allows the access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles in good overall yields. As no efficient synthetic routes to 2,3-dihaloanilines have been described in the literature, different approaches to the preparation of these 1,2,3-functionalized aromatic precursors are now presented. The most general one involves a Smiles rearrangement from the corresponding 2,3-dihalophenols and allows the preparation of 2,3-dihaloanilides in a straightforward and synthetically useful manner.