87133-21-9Relevant articles and documents
Synthesis and molecular shuttling of [2]rotaxanes under mild conditions
Tukada, Hideyuki,Hiraki, Toshihiro,Nakamura, Hiroshi
, p. 630 - 632 (2013)
[2]Rotaxanes constructed with an ethereal end-capped axle and a dibenzo-24-crown-8 wheel were synthesized from pseudorotaxanes bearing an alcoholic terminus and diaryldiazomethanes using diphenyl phosphate as a catalyst. The reaction proceeded at room temperature in nonpolar solvents within several hours. The [2]rotaxanes thus obtained behaved as ammonium salts derived from a very strong base such as DBU. Thus, the amine form of the [2]rotaxane reacted with a weak acid, CO2H2O, to give a hydrogencarbonate salt of the [2]rotaxane, which turned back to the amine form after drying followed by evacuation.
3,4,5-trisubstituted aryl nitrone compounds, pharmaceutical compositions containing the same and methods for treating inflammation
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Page column 17-18, (2008/06/13)
Disclosed are 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have the formula: where R1-R4are as defined in the specification. The disclosed compositions are useful as therapeutics for inflammation-related conditions in mammals, such as arthritis, and as analytical reagents for detecting free radicals.