87151-63-1 Usage
Description
(+/-)-1-oxaspiro[4,5]dec-7-ene is a bicyclic chemical compound that belongs to the spiroketal group. It features a unique spiroannulated structure with a seven-membered spiro ring system and a double bond. (+/-)-1-oxaspiro[4,5]dec-7-ene is known for its versatile reactivity and structural features, making it valuable and interesting for chemical research and development.
Uses
Used in Organic Synthesis:
(+/-)-1-oxaspiro[4,5]dec-7-ene is used as a building block in the preparation of natural products and bioactive compounds. Its unique structure and reactivity make it a valuable component in the synthesis of various organic compounds.
Used in Pharmaceutical Synthesis:
(+/-)-1-oxaspiro[4,5]dec-7-ene serves as a starting material for the synthesis of pharmaceuticals. Its structural features and reactivity contribute to the development of new drugs and medicinal compounds.
Used in Agrochemical Synthesis:
(+/-)-1-oxaspiro[4,5]dec-7-ene is also utilized as a starting material for the synthesis of agrochemicals, playing a role in the development of pesticides, herbicides, and other agricultural products.
Used in Fragrance and Flavor Industry:
Due to its unique structure and aromatic properties, (+/-)-1-oxaspiro[4,5]dec-7-ene has potential applications in the fragrance and flavor industry. It can be used to create novel scents and flavors for various consumer products.
Check Digit Verification of cas no
The CAS Registry Mumber 87151-63-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,1,5 and 1 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 87151-63:
(7*8)+(6*7)+(5*1)+(4*5)+(3*1)+(2*6)+(1*3)=141
141 % 10 = 1
So 87151-63-1 is a valid CAS Registry Number.
87151-63-1Relevant articles and documents
A practical synthesis of the kappa opioid receptor selective agonist (+)-5R,7S,8S-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxospiro[4,5]dec-8-yl] benzeneacetamide (U69,593)
McElroy, Timothy,Thomas, James B.,Brine, George A.,Navarro, Hernan A.,Deschamps, Jeffrey,Carroll, F. Ivy
, p. 943 - 947 (2008/12/23)
A novel approach to the synthesis of the kappa opioid receptor agonist U69,593 has been developed. This approach improves upon current literature methods by substituting stable and isolable cyclic sulfates for the unstable epoxides. The new approach provides access to gram quantities of the target compound and displays excellent control of the relative stereochemistry. The absolute stereochemistry as well as biological activity of the U69,593 produced by this new method was verified using X-ray crystal structure analysis and binding assays for the kappa opioid receptor. Georg Thieme Verlag Stuttgart.
Analgesic 1-oxa-, aza- and thia-spirocyclic compounds
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, (2008/06/13)
Mono-Oxa-, thiaspirocyclic-benzene-acetamide and -benzamide compounds of the formula STR1 wherein p, n, m, A, E, R, R1, R2, X, Y and Z are as defined in the specification, e.g., (±)-(5α,7α,9β)-3,4-dichloro-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]benzeneacetamide, and the pharmacologically acceptable salts thereof, are useful as analgesic compounds having low physical dependence liability, compared to morphine and methodone, and low dysphoria side effects. Some of these compounds have potent analgesic activity when administered orally, and some have low CNS sedative side effects. Pharmaceutical compositions and methods for using these compounds as analgesics are disclosed. Processes for preparing this class of compounds are also disclosed.